業績集

令和6（2024）年度

2024年度研究費取得状況

論文・著書など

論文（欧文）

1. Metayer C, Spector LG, Scheurer ME, Jeon S, Scott RJ, Takagi M, Clavel J, Manabe A, Ma X, Hailu EM, Lupo PJ, Urayama KY, Bonaventure A, Kato M, Meirhaeghe A, Chiang CWK, Morimoto LM, Wiemels JL. Folate Metabolism and Risk of Childhood Acute Lymphoblastic Leukemia: A Genetic Pathway Analysis from the Childhood Cancer and Leukemia International Consortium. Cancer Epidemiol Biomarkers Prev. 2024;33(9):1248-52. Epub 2024/06/21. doi: 10.1158/1055-9965.Epi-24-0189. PubMed PMID: 38904462; PubMed Central PMCID: PMCPMC11369612.
2. Tsumura Y, Muramatsu H, Tetsuka N, Imaizumi T, Sato K, Inoue K, Motomura Y, Cho Y, Yamashita D, Sajiki D, Maemura R, Yamamori A, Imaya M, Wakamatsu M, Narita K, Kataoka S, Hamada M, Taniguchi R, Nishikawa E, Narita A, Nishio N, Kojima S, Hoshino Y, Takahashi Y. A Japanese retrospective study of non-tuberculous mycobacterial infection in children, adolescents, and young adult patients with hematologic-oncologic diseases. Haematologica. 2024;109(9):2988-97. Epub 2023/10/26. doi: 10.3324/haematol.2023.283636. PubMed PMID: 37881854; PubMed Central PMCID: PMCPMC11367237.
3. Nakamura A, Nomura S, Hara S, Thamamongood T, Maehara T, Nariai T, Khairullah S, Tan KS, Azuma K, Chida-Nagai A, Furutani Y, Hori T, Yamaguchi K, Kawamata T, Roder C, Akagawa H. Whole-exome sequencing reveals the genetic causes and modifiers of moyamoya syndrome. Sci Rep. 2024;14(1):22720. Epub 2024/10/05. doi: 10.1038/s41598-024-72043-5. PubMed PMID: 39367156; PubMed Central PMCID: PMCPMC11452616.
4. Kimura S, Park CS, Montefiori LE, Iacobucci I, Pölönen P, Gao Q, Arnold ED, Attarbaschi A, Brown A, Buldini B, Caldwell KJ, Chang Y, Chen C, Cheng C, Cheng Z, Choi J, Conter V, Crews KR, de Groot-Kruseman HA, Deguchi T, Eguchi M, Muhle HE, Elitzur S, Escherich G, Freeman BB 3rd, Gu Z, Han K, Horibe K, Imamura T, Jeha S, Kato M, Chiew KH, Khan T, Kicinski M, Köhrer S, Kornblau SM, Kotecha RS, Li CK, Liu YC, Locatelli F, Luger SM, Paietta EM, Manabe A, Marquart HV, Masetti R, Maybury M, Mazilier P, Meijerink JPP, Mitchell S, Miyamura T, Moore AS, Oshima K, Pawinska-Wasikowska K, Pieters R, Prater MS, Pruett-Miller SM, Pui CH, Qu C, Reiterova M, Reyes N, Roberts KG, Rowe JM, Sato A, Schmiegelow K, Schrappe M, Shen S, Skoczeń S, Spinelli O, Stary J, Svaton M, Takagi M, Takita J, Tang Y, Teachey DT, Thomas PG, Tomizawa D, Trka J, Varotto E, Vincent TL, Yang JJ, Yeoh AEJ, Zhou Y, Zimmermann M, Inaba H, Mullighan CG. Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk. Cancer Discov. 2024;14(10):1838-59. Epub 2024/06/25. doi: 10.1158/2159-8290.Cd-23-1452. PubMed PMID: 38916500; PubMed Central PMCID: PMCPMC11452281.
5. Honda S, Kawakita I, Okumura K, Ara M, Goto R, Takeda A, Shimamura T, Kawahara I, Taketomi A. Unusual rapid development of portopulmonary hypertension after shunt closure for congenital portosystemic shunt. J Paediatr Child Health. 2024;60(10):606-9. Epub 2024/08/06. doi: 10.1111/jpc.16636. PubMed PMID: 39105396.
6. Terashita Y, Iguchi A, Sugiyama M, Cho Y, Goudarzi H, Yokota I, Manabe A. Serum 5-S-cysteinyldopa as a predictive biomarker for stem cell transplantation-related complications in children and young adults. Blood Cell Ther. 2024;7(4):111-7. Epub 2024/12/09. doi: 10.31547/bct-2024-001. PubMed PMID: 39651064; PubMed Central PMCID: PMCPMC11620987.
7. Sato T, Kihara Y, Ishiguro K, Shichiji M, Murakami T, Nagata S, Shimada E, Inai K, Takeda A, Ishigaki K. Cross-sectional Study of the Association between Plasma Brain Natriuretic Peptide Levels and Left Ventricular Shortening Fraction in Fukuyama Congenital Muscular Dystrophy. Tohoku J Exp Med. 2024. Epub 2024/11/21. doi: 10.1620/tjem.2024.J137. PubMed PMID: 39566997.
8. Sakaguchi H, Taga T, Ishida H, Hama A, Okamoto Y, Sano H, Sato M, Koga Y, Koh K, Iwasaki F, Yoshida N, Cho Y, Okada K, Watanabe K, Watanabe A, Hasegawa D, Noguchi M, Hashii Y, Matsumoto K, Tabuchi K; Pediatric Acute Myeloid Leukemia Working Group of Japanese Society for Transplantation and Cellular Therapy. Salvage hematopoietic cell transplantation for children with acute myeloid leukemia relapsed after first transplantation: a Japanese national registry study. Bone Marrow Transplant. 2024;59(11):1621-4. Epub 2024/08/23. doi: 10.1038/s41409-024-02396-y. PubMed PMID: 39174743.
9. Kinoshita M, Saito Y, Otani K, Uehara Y, Nagasawa S, Nakagawa M, Yamada A, Kamimura S, Moritake H. Mitochondrial dynamics as a potential therapeutic target in acute myeloid leukemia. Int J Hematol. 2024;120(5):601-12. Epub 2024/09/17. doi: 10.1007/s12185-024-03843-8. PubMed PMID: 39283580.
10. Inoue S, Kondo A, Inoki Y, Ichikawa Y, Tanaka Y, Ueda C, Kitakado H, Suzuki R, Okada E, Sakakibara N, Horinouchi T, Nozu K. Evaluation of pathogenicity of WT1 intron variants by in vitro splicing analysis. Clin Exp Nephrol. 2024;28(11):1075-81. Epub 2024/06/15. doi: 10.1007/s10157-024-02510-w. PubMed PMID: 38877226; PubMed Central PMCID: PMCPMC11568005.
11. Miyamoto S, Niizato D, Tomomasa D, Nishimura A, Hoshino A, Kamiya T, Isoda T, Takagi M, Kajiwara M, Azumi S, Hirabayashi S, Sakamoto K, Kishimoto K, Miyamura T, Umeda K, Hirose A, Keino D, Yanagimachi M, Kanda K, Sakai Y, Ikawa Y, Watanabe K, Tanaka K, Mori T, Ichinohe T, Sakaguchi H, Morio T, Kanegane H. Allogeneic Hematopoietic cell Transplantation Using Alemtuzumab in Asian Patients with Inborn Errors of Immunity. J Clin Immunol. 2024;44(6):126. Epub 2024/05/22. doi: 10.1007/s10875-024-01734-5. PubMed PMID: 38773000.
12. Chida-Nagai A, Sato H, Yamazawa H, Takeda A, Yonemoto N, Tahara Y, lkeda T. Impact of the COVID-19 pandemic on pediatric out-of-hospital cardiac arrest outcomes in Japan. Sci Rep. 2024;14(1):11246. Epub 2024/05/17. doi: 10.1038/s41598-024-61650-x. PubMed PMID: 38755175; PubMed Central PMCID: PMCPMC11099039.
13. Chida-Nagai A, Akagawa H, Sawai S, Ma YJ, Yakuwa S, Muneuchi J, Yasuda K, Yamazawa H, Yamamoto T, Takakuwa E, Tomaru U, Furutani Y, Kato T, Harada G, Inai K, Nakanishi T, Manabe A, Takeda A, Jing ZC. Identification of Prostaglandin I2 Synthase Rare Variants in Patients With Williams Syndrome and Severe Peripheral Pulmonary Stenosis. J Am Heart Assoc. 2024 May 7;13(9):e032872. doi: 10.1161/JAHA.123.032872. Epub 2024 Apr 19. PMID: 38639351; PMCID: PMC11179920.
14. Iwata H, Yamaguchi T, Kishi R. Transforming Large Birth Cohorts and Graduate Education: Challenges and Strategies. Intern Med. 2025;64(9):1448. Epub 2024/09/12. doi: 10.2169/internalmedicine.4418-24. PubMed PMID: 39261063.
15. Yamanaka H, Ueki M, Kikuchi K, Yakuwa S. Chronic Ileum Obstruction, Granulation, and Ulceration With IgG4-Positive Plasma Cell Infiltration in a Six-Year-Old Girl With 21trisomy. Cureus. 2024;16(5):e60177. Epub 2024/06/13. doi: 10.7759/cureus.60177. PubMed PMID: 38868234; PubMed Central PMCID: PMCPMC11167512.
16. Morita S, Nomura S, Azuma K, Chida-Nagai A, Furutani Y, Inai K, Inoue T, Niimi Y, Iizuka Y, Tsutsumi Y, Ishizaki R, Yamagishi H, Kawamata T, Akagawa H. Functional characterization of variants found in Japanese patients with hereditary hemorrhagic telangiectasia. Clin Genet. 2024 May;105(5):543-548. doi: 10.1111/cge.14483. Epub 2024 Jan 15. PMID: 38225712.
17. Mizushima M, Kawabori M, Yamazaki K, Egawa K, Fujimura M. Ommaya reservoir placement using ultrasound guidance via anterior fontanelle combined with frameless electromagnetic neuronavigation in patients with mucopolysaccharidosis type 2: Case reports and review of the literature. Childs Nerv Syst. 2024;40(5):1603-7. Epub 2024/01/02. doi: 10.1007/s00381-023-06265-9. PubMed PMID: 38165414.
18. Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Hori K, Hoshino M, Nakao A, Mori Y, Okabe S, Matsushita M, Urbach A, Katayama Y, Matsumoto A, Nakayama KI, Katori S, Sato T, Iwasato T, Nakamura H, Goshima Y, Raveau M, Tatsukawa T, Yamakawa K, Takahashi N, Kasai H, Inazawa J, Nobuhisa I, Kagawa T, Taga T, Darwish M, Nishizono H, Takao K, Sapkota K, Nakazawa K, Takagi T, Fujisawa H, Sugimura Y, Yamanishi K, Rajagopal L, Hannah ND, Meltzer HY, Yamamoto T, Wakatsuki S, Araki T, Tabuchi K, Numakawa T, Kunugi H, Huang FL, Hayata-Takano A, Hashimoto H, Tamada K, Takumi T, Kasahara T, Kato T, Graef IA, Crabtree GR, Asaoka N, Hatakama H, Kaneko S, Kohno T, Hattori M, Hoshiba Y, Miyake R, Obi-Nagata K, Hayashi-Takagi A, Becker LJ, Yalcin I, Hagino Y, Kotajima-Murakami H, Moriya Y, Ikeda K, Kim H, Kaang BK, Otabi H, Yoshida Y, Toyoda A, Komiyama NH, Grant SGN, Ida-Eto M, Narita M, Matsumoto KI, Okuda-Ashitaka E, Ohmori I, Shimada T, Yamagata K, Ageta H, Tsuchida K, Inokuchi K, Sassa T, Kihara A, Fukasawa M, Usuda N, Katano T, Tanaka T, Yoshihara Y, Igarashi M, Hayashi T, Ishikawa K, Yamamoto S, Nishimura N, Nakada K, Hirotsune S, Egawa K, Higashisaka K, Tsutsumi Y, Nishihara S, Sugo N, Yagi T, Ueno N, Yamamoto T, Kubo Y, Ohashi R, Shiina N, Shimizu K, Higo-Yamamoto S, Oishi K, Mori H, Furuse T, Tamura M, Shirakawa H, Sato DX, Inoue YU, Inoue T, Komine Y, Yamamori T, Sakimura K, Miyakawa T. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. Elife. 2024 Mar 26;12:RP89376. doi: 10.7554/eLife.89376. PMID: 38529532; PMCID: PMC10965225.
19. Kobayashi S, Saijo Y, Iwata H, Yamaguchi T, Tamura N, Itoh M, Tojo M, Ito Y, Kishi R; Japan Environment and Children’s Study (JECS) Group. Association Between the Occupation of Pregnant Women's Partners and Risks of Infant Low Birth Weight and Preterm Birth in a Prospective Birth Cohort: The Japan Environment and Children's Study. J Occup Environ Med. 2025 Mar 1;67(3):161-170. doi: 10.1097/JOM.0000000000003279. Epub 2024 Nov 19. PMID: 39805128.
20. Ueki M, Hirabayashi S, Honda Y, Takezaki S, Ohata H, Abdrabou SSMA, Sawai S, Terashita Y, Cho Y, Muramatsu H, Izawa K, Yasumi T, Takahashi Y, Yamada M, Manabe A. Increased response to granulocyte-macrophage colony-stimulating factor in peripheral blood cells and transient manifestations mimicking juvenile myelomonocytic leukemia in a male patient with NEMO deficiency caused by a deep intronic pathogenic variant of IKBKG. Immunol Med. 2025 Mar;48(1):94-101. doi: 10.1080/25785826.2024.2422639. Epub 2024 Nov 1. PMID: 39485070.
21. Ueda Y, Egawa K, Kawamura K, Ochi N, Goto T, Kimura S, Narugami M, Nakakubo S, Nakajima M, Manabe A, Shiraishi H. Nusinersen induces detectable changes in compound motor action potential response in spinal muscular atrophy type 1 patients with severe impairment of motor function. Brain Dev. 2024;46(3):149-53. Epub 2023/12/17. doi: 10.1016/j.braindev.2023.12.001. PubMed PMID: 38103972.
22. Shiraishi M, Sasaki D, Hibino M, Takeda A, Harashima H, Yamada Y. Human cardiosphere-derived cells with activated mitochondria for better myocardial regenerative therapy. J Control Release. 2024;367:486-99. Epub 2024/02/01. doi: 10.1016/j.jconrel.2024.01.058. PubMed PMID: 38295995.
23. Morikawa S, Tanabe K, Kaneko N, Hishimura N, Nakamura A. Comprehensive overview of disease models for Wolfram syndrome: toward effective treatments. Mamm Genome. 2024;35(1):1-12. Epub 2024/02/14. doi: 10.1007/s00335-023-10028-x. PubMed PMID: 38351344.
24. Hosokawa C, Hotta K, Okamoto T, Cho Y, Hirose T, Iwahara N, Manabe A, Shinohara N. Prophylactic bilateral nephrectomy and preemptive kidney transplantation for Denys-Drash syndrome prior to development of kidney failure. Pediatr Nephrol. 2024;39(3):905-9. Epub 2023/08/13. doi: 10.1007/s00467-023-06113-7. PubMed PMID: 37572117.
25. Fujita Y, Chida-Nagai A, Takeda A. Tricuspid stenosis due to pectus excavatum in a paediatric patient with trisomy 21. Eur Heart J Case Rep. 2024;8(3):ytae104. Epub 2024/03/04. doi: 10.1093/ehjcr/ytae104. PubMed PMID: 38434211; PubMed Central PMCID: PMCPMC10908392.
26. Ono R, Sakamoto K, Kudo K, Sato A, Kudo K, Fujino H, Kawahara Y, Hashimoto H, Doi T, Yanagisawa R, Kawamata T, Miyazaki O, Nakazawa A, Ota Y, Kanegane H, Nakazawa Y, Horibe K, Saito AM, Manabe A, Usuki K, Kiyoi H, Morimoto A, Tojo A, Shioda Y. Phase II study in children and adults under 40 years with newly diagnosed Langerhans cell histiocytosis: protocol for an LCH-19-MSMFB clinical trial in Japan. BMJ Open. 2024 Jun 23;14(6):e084159. doi: 10.1136/bmjopen-2024-084159. PMID: 38910000; PMCID: PMC11328669.
27. Takeda Y, Ueki M, Matsuhiro J, Walinda E, Tanaka T, Yamada M, Fujita H, Takezaki S, Kobayashi I, Tamaki S, Nagata S, Miyake N, Matsumoto N, Osawa M, Yasumi T, Heike T, Ohtake F, Saito MK, Toguchida J, Takita J, Ariga T, Iwai K. A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome. J Exp Med. 2024 Jun 3;221(6):e20231941. doi: 10.1084/jem.20231941. Epub 2024 Apr 23. PMID: 38652464; PMCID: PMC11040501.
28. Nakamura Y, Kobayashi S, Cho K, Itoh S, Miyashita C, Yamaguchi T, Iwata H, Tamura N, Saijo Y, Ito Y, Seto Y, Honjo R, Ando A, Furuse Y, Manabe A, Kishi R; Japan Environment and Children’s Study (JECS) Group. Prenatal metal concentrations and physical abnormalities in the Japan Environment and Children's Study. Pediatr Res. 2024 Jun;95(7):1875-1882. doi: 10.1038/s41390-023-02851-4. Epub 2023 Oct 19. Erratum in: Pediatr Res. 2024 May;95(6):1659-1661. doi: 10.1038/s41390-024-03099-2. PMID: 37857850.
29. Nakamura K, Terashita Y, Manabe A, Suzuki N. Survey of Transitional Care Between Pediatrics and Obstetrics/Gynecology in Japan. J Adolesc Young Adult Oncol. 2024;13(3):523-33. Epub 2024/02/28. doi: 10.1089/jayao.2023.0017. PubMed PMID: 38416604.
30. Rohner K, Marlais M, Ahn YH, Ali A, Alsharief A, Novak AB, Brambilla M, Cakici EK, Candan C, Canpolat N, Chan EY, Decramer S, Didsbury M, Durao F, Durkan AM, Düzova A, Forbes T, Gracchi V, Güngör T, Horinouchi T, Kasap Demir B, Kobayashi Y, Koskela M, Kurt-Sukur ED, La Scola C, Langan D, Li X, Malgieri G, Mastrangelo A, Min J, Mizerska-Wasiak M, Moussaoui N, Noyan A, Nuutinen M, O'Gormon J, Okamoto T, Oni L, Oosterveld M, Pańczyk-Tomaszewska M, Parmaksiz G, Pasini A, Rianthavorn P, Roelofs J, Shen Y, Sinha R, Topaloglu R, Torres DD, Udagawa T, Wennerström M, Yap YC, Tullus K. Outcome of immunosuppression in children with IgA vasculitis-related nephritis. Nephrol Dial Transplant. 2024 Jul 31;39(8):1299-1309. doi: 10.1093/ndt/gfae009. PMID: 38211969.
31. Hiramatsu Y, Takahashi K, Shimomura M, Taniguchi K, Okura Y, Nawate M, Takahashi Y, Kobayashi I. Hypothermia, bradycardia, and hypotension during glucocorticoid or cyclosporine A therapy in a boy with Kikuchi-Fujimoto disease. Mod Rheumatol Case Rep. 2024;8(2):352-6. Epub 2024/05/23. doi: 10.1093/mrcr/rxae023. PubMed PMID: 38780240.
32. Sato I, Hibino M, Takeda A, Harashima H, Yamada Y. Activation of Mitochondrial Oxygen Consumption Rate by Delivering Coenzyme Q(10) to Mitochondria of Rat Skeletal Muscle Cell (L6). J Pharm Sci. 2024;113(7):1836-43. Epub 2024/02/08. doi: 10.1016/j.xphs.2024.01.020. PubMed PMID: 38325738.
33. Makimoto A, Fujisaki H, Matsumoto K, Takahashi Y, Cho Y, Morikawa Y, Yuza Y, Tajiri T, Iehara T. Retinoid Therapy for Neuroblastoma: Historical Overview, Regulatory Challenges, and Prospects. Cancers (Basel). 2024;16(3). Epub 2024/02/10. doi: 10.3390/cancers16030544. PubMed PMID: 38339295; PubMed Central PMCID: PMCPMC10854948.
34. Izumi G, Shida S, Kobayashi N, Yamazawa H, Takeda A. Initial Holter Electrocardiogram Index to Predict the Burden of Subsequent Persistent Premature Ventricular Complex in Childhood. Circ J. 2025;89(2):234-9. Epub 2024/07/22. doi: 10.1253/circj.CJ-24-0438. PubMed PMID: 39034112.
35. Ishida H, Tsujimoto SI, Hasegawa D, Sakaguchi H, Yamamoto S, Yanagimachi M, Koh K, Watanabe A, Hama A, Cho Y, Watanabe K, Noguchi M, Takeuchi M, Takita J, Washio K, Kato K, Koike T, Hashii Y, Tabuchi K, Hino M, Atsuta Y, Okamoto Y. Optimizing transplantation procedures through identification of prognostic factors in second remission for children with acute myeloid leukemia with no prior history of transplant. Haematologica. 2024 Jan 1;109(1):312-317. doi: 10.3324/haematol.2023.283203. PMID: 37470138; PMCID: PMC10772516.
36. Shiraishi H, Egawa K, Murakami K, Nakajima M, Ueda Y, Nakakubo S, Narugami M, Kimura S, Goto T, Hiramatsu Y, Murakami M. Transcutaneous auricular vagus nerve stimulation therapy in patients with cognitively preserved structural focal epilepsy: A case series report. Brain Dev. 2024 Jan;46(1):49-56. doi: 10.1016/j.braindev.2023.08.007. Epub 2023 Aug 30. PMID: 37657962.
37. Sawai S, Oda Y, Saito Y, Kuwabara T, Wang L, Tanei ZI, Hirabayashi S, Tsuda M, Gong JP, Manabe A, Tanaka S. Analysis of synthetic polymer hydrogel-based generation of leukemia stem cells. Biochem Biophys Res Commun. 2025;744:151149. Epub 2024/12/20. doi: 10.1016/j.bbrc.2024.151149. PubMed PMID: 39700762.
38. Sakashita K, Yoshida N, Muramatsu H, Ohtsuka Y, Watanabe K, Yabe M, Kakuda H, Honda Y, Watanabe T, Haba M, Ohmori S, Matsuda K, Yuza Y, Saito A, Horibe K, Adachi S, Manabe A. Allogeneic Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia with a Busulfan, Fludarabine, and Melphalan Regimen: JPLSG JMML-11. Transplant Cell Ther. 2024 Jan;30(1):105.e1-105.e10. doi: 10.1016/j.jtct.2023.10.002. Epub 2023 Oct 7. PMID: 37806448.
39. Kimoto Y, Hirata K, Hirano S, Wada K, Moriichi A, Ito Y, Cho K, Mizuno K, Toyoshima K, Kushima R, Ishii N, Yamaguchi T, Hashimoto K, Yada Y, Kono Y. Post-Discharge Growth Among Extremely Preterm Infants With or Without Bronchopulmonary Dysplasia. Pediatr Pulmonol. 2025 Jan;60(1):e27388. doi: 10.1002/ppul.27388. Epub 2024 Nov 8. PMID: 39513637.
40. Iwata H, Kobayashi S, Itoh M, Itoh S, Mesfin Ketema R, Tamura N, Miyashita C, Yamaguchi T, Yamazaki K, Masuda H, Ait Bamai Y, Saijo Y, Ito Y, Nakayama SF, Kamijima M, Kishi R; Japan Environment, Children's Study JECS Group. The association between prenatal per-and polyfluoroalkyl substance levels and Kawasaki disease among children of up to 4 years of age: A prospective birth cohort of the Japan Environment and Children's study. Environ Int. 2024 Jan;183:108321. doi: 10.1016/j.envint.2023.108321. Epub 2023 Nov 11. PMID: 38061246.
41. Kato M, Okamoto Y, Imamura T, Kada A, Saito AM, Iijima-Yamashita Y, Deguchi T, Ohki K, Fukushima T, Anami K, Sanada M, Taki T, Hashii Y, Inukai T, Kiyokawa N, Kosaka Y, Yoshida N, Yuza Y, Yanagimachi M, Watanabe K, Sato A, Imai C, Taga T, Adachi S, Horibe K, Manabe A, Koh K. JCCG ALL-B12: Evaluation of Intensified Therapies With Vincristine/Dexamethasone Pulses and Asparaginase and Augmented High-Dose Methotrexate for Pediatric B-ALL. J Clin Oncol. 2025 Feb 10;43(5):567-577. doi: 10.1200/JCO.24.00811. Epub 2024 Nov 12. PMID: 39531610; PMCID: PMC11809717.
42. Kobayashi S, Saijo Y, Itoh M, Tamura N, Tojo M, Iwata H, Yamaguchi T, Ito Y, Kishi R; Japan Environment and Children's Study (JECS) Group. Effects of the Maternal Work Environment on Psychological Distress During Pregnancy: A Cross-sectional Research-The Japan Environment and Children's Study. J Occup Environ Med. 2025 Feb 1;67(2):89-99. doi: 10.1097/JOM.0000000000003276. Epub 2024 Nov 19. PMID: 39805142.
43. Yamaguchi A, Hirabayashi S, Niki K, Kagami K, Terashita Y, Cho Y, Manabe A, Sugawara M, Takekuma Y. Comparison of busulfan pharmacokinetics between four-times-daily and once-daily administration in pediatric patients: a preliminary prospective observational trial. Int J Hematol. 2025 Feb;121(2):244-251. doi: 10.1007/s12185-024-03891-0. Epub 2024 Dec 3. PMID: 39625679.
44. Ueda Y, Furugen A, Kobayashi M, Sato Y, Ueda Y, Hayashi A, Goto T, Kimura S, Narugami M, Nakakubo S, Nakajima M, Egawa K, Okamoto T, Manabe A, Shiraishi H. Use of lacosamide for focal epilepsy in a child with kidney failure undergoing peritoneal dialysis. Brain Dev. 2024 Feb;46(2):114-117. doi: 10.1016/j.braindev.2023.10.003. Epub 2023 Oct 31. PMID: 37914622.
45. Tojo M, Iwata H, Tamura N, Yamaguchi T, Tsuchiya KJ, Suyama S, Obara T, Nakai A, Yoshikawa T, Yamagata T, Itoh M, Yamazaki K, Kobayashi S, Kishi R. Association between small for gestational age and motor coordination difficulties in children aged 5-6 years: Insights from the Hokkaido Study on Environment and Children's Health. Brain Dev. 2025;47(1):104296. Epub 2024/11/16. doi: 10.1016/j.braindev.2024.10.004. PubMed PMID: 39546826.
46. Poudel K, Kobayashi S, Iwata H, Tojo M, Yamaguchi T, Yamazaki K, Tamura N, Itoh M, Obara T, Kuriyama S, Kishi R. Hokkaido birth cohort study in Japan on the growth trajectory of children born with low birth weight until 7 years of age. Early Hum Dev. 2024 Feb;189:105925. doi: 10.1016/j.earlhumdev.2023.105925. Epub 2023 Dec 26. PMID: 38199046.
47. Maezawa T, Suzuki N, Takeuchi H, Nishioka M, Hidaka M, Manabe A, Koga Y, Kawaguchi H, Sasahara Y, Tachibana M, Iwamoto S, Horie A, Hiramatsu H, Kato M, Harada M, Yuza Y, Hirayama M, Takita J, Ikeda T, Matsumoto K. Challenges to Widespread Use of Fertility Preservation Facilities for Pediatric Cancer Patients in Japan. J Adolesc Young Adult Oncol. 2024;13(1):197-202. Epub 2023/08/03. doi: 10.1089/jayao.2023.0059. PubMed PMID: 37535825.
48. Kikuchi K, Kuki I, Nishiyama M, Ueda Y, Matsuura R, Shiohama T, Nagase H, Akiyama T, Sugai K, Hayashi K, Murakami K, Yamamoto H, Fukuda T, Kashiwagi M, Maegaki Y. Japanese guidelines for treatment of pediatric status epilepticus - 2023. Brain Dev. 2025;47(1):104306. Epub 2024/12/04. doi: 10.1016/j.braindev.2024.104306. PubMed PMID: 39626562.
49. Kato I, Tomizawa D, Kato M, Hirabayashi S, Manabe A, Irie M, Sasahara Y, Arakawa Y, Koh K, Sakaguchi H, Sugiyama M, Ogawa C, Kamiya T, Saito S, Nakazawa Y, Nishio N, Takahashi Y, Iwai N, Adachi S, Takita J, Miyamura T, Yokoyama S, Oba U, Ueda T, Koga Y, Hiramatsu H. Real-world Outcomes of Commercial Tisagenlecleucel for Children, Adolescents, and Young Adults With Acute Lymphoblastic Leukemia in Japan. Transplant Cell Ther. 2025 Feb;31(2):86-96. doi: 10.1016/j.jtct.2024.11.016. Epub 2024 Nov 30. PMID: 39617098.
50. Izumi G, Takeda A, Okamoto T, Shida S, Matsuo H. A case of tachycardia-induced acute kidney injury by renal hypouricemia. J Cardiol Cases. 2024;29(2):59-62. Epub 2024/02/16. doi: 10.1016/j.jccase.2023.10.009. PubMed PMID: 38362583; PubMed Central PMCID: PMCPMC10865112.
51. Honjo R, Cho K, Hashimoto K, Takeda K, Seto Y, Kaneshi Y, Furuse Y, Manabe A. Neonatal-onset pulmonary alveolar proteinosis is a phenotype associated with poor outcomes in surfactant protein-C disorder. Early Hum Dev. 2024;189:105930. Epub 2024/01/11. doi: 10.1016/j.earlhumdev.2023.105930. PubMed PMID: 38199047.
52. Okura Y, Hiramatsu Y, Shimomura M, Taniguchi K, Nawate M, Takahashi Y, Ueki M, Takezaki S, Kobayashi I. Pyoderma gangrenosum arising at the site of BCG immunization in a nine-month-old girl. Immunol Med. 2024:1-6. Epub 2024/12/26. doi: 10.1080/25785826.2024.2445388. PubMed PMID: 39724055.
53. Itoh M, Kobayashi S, Nishihara S, Miyashita C, Yamazaki K, Tamura N, Suyama S, Ikeda A, Itoh S, Ait Bamai Y, Yamaguchi T, Masuda H, Hanley S, Kishi R. Association between prenatal tobacco exposure and attention-deficit/hyperactivity disorder related characteristics at 6 and 8 years: a birth cohort in Japan. BMJ Open. 2024;14(12):e087406. Epub 2024/12/27. doi: 10.1136/bmjopen-2024-087406. PubMed PMID: 39725438; PubMed Central PMCID: PMCPMC11683938.
54. Yamanaka J, Ogawa C, Arakawa A, Deguchi T, Hori T, Kiyokawa N, Ueki H, Nishi M, Mochizuki S, Nishikawa T, Kumamoto T, Nishiuchi R, Kikuta A, Yamamoto S, Koh K, Hasegawa D, Ogawa A, Watanabe K, Sato A, Saito AM, Watanabe T, Manabe A, Horibe K, Goto H, Toyoda H. Outcomes in children with first-relapsed acute lymphoblastic leukemia in Japan: Results from JCCG Study JPLSG-ALL-R08. Pediatr Blood Cancer. 2024;71(12):e31319. Epub 2024/09/15 21:16. doi: 10.1002/pbc.31319. PubMed PMID: 39267231.
55. Ono M, Takai Y, Harada M, Horie A, Dai Y, Kikuchi E, Miyachi M, Yamamoto T, Fujii N, Kajiyama H, Manabe A, Yasuoka T, Katsuragi S, Mekaru K, Maezawa T, Horage Y, Kataoka S, Nakayama R, Nakajima TE, Kimura F, Shimizu C, Sugimoto K, Takae S, Yumura Y, Nishi H, Furui T, Morishige KI, Watanabe C, Osuga Y, Suzuki N. Out-of-pocket fertility preservation expenses: data from a Japanese nationwide multicenter survey. Int J Clin Oncol. 2024;29(12):1959-66. Epub 2024/09/05. doi: 10.1007/s10147-024-02614-z. PubMed PMID: 39231915; PubMed Central PMCID: PMCPMC11588863.
56. Matsukawa T, Onozawa M, Kondo T, Kanaya M, Hidaka D, Ota S, Mori A, Shigematsu A, Miyagishima T, Kakinoki Y, Hashiguchi J, Yamamoto S, Yamamoto M, Wakasa K, Takahata M, Ishihara T, Haseyama Y, Fujimi A, Igarashi T, Sarashina T, Iyama S, Kobayashi R, Sakai H, Fujimoto K, Inamura J, Kanisawa Y, Hirabayashi S, Endo T, Hashimoto D, Teshima T. FLT3 inhibitors and hematopoietic cell transplantation prolong survival in patients with FLT3-ITD-positive AML. Ann Hematol. 2024;103(12):5333-40. Epub 2024/12/01. doi: 10.1007/s00277-024-06125-9. PubMed PMID: 39614924.
57. Yano T, Takeda A, Murayama K. A hidden cause of middle-aged onset heart failure with preserved ejection fraction: a GTPBP3 variant. Eur Heart J. 2024;45(30):2794. Epub 2024/05/24. doi: 10.1093/eurheartj/ehae309. PubMed PMID: 38785384.
58. Akagi T, Saijo Y, Yoshioka E, Sato Y, Nakanishi K, Kato Y, Nagaya K, Takahashi S, Ito Y, Iwata H, Yamaguchi T, Miyashita C, Ito S, Kishi R. Association between maternal multimorbidity and neurodevelopment of offspring: a prospective birth cohort study from the Japan Environment and Children's Study. BMJ Open. 2024;14(8):e082585. Epub 2024/08/04. doi: 10.1136/bmjopen-2023-082585. PubMed PMID: 39097305; PubMed Central PMCID: PMCPMC11345530.
59. Ishida H, Kawahara Y, Tomizawa D, Okamoto Y, Hama A, Cho Y, Koh K, Koga Y, Yoshida N, Sato M, Terui K, Miyagawa N, Watanabe A, Takita J, Kobayashi R, Yamamoto M, Watanabe K, Okada K, Kato K, Matsumoto K, Hino M, Tabuchi K, Sakaguchi H. A higher CD34 + cell dose correlates with better event-free survival after KIR-ligand mismatched cord blood transplantation for childhood acute myeloid leukemia. J Hematol Oncol. 2024;17(1):24. Epub 2024/04/29. doi: 10.1186/s13045-024-01548-3. PubMed PMID: 38679709; PubMed Central PMCID: PMCPMC11057148.
60. Morikawa S, Ko HL, Ren EC, Hara K, Kaneko N, Hishimura N, Nakamura A, Manabe A. Functional Analysis of a Novel HNF4A Variant Identified in a Patient With MODY1. J Endocr Soc. 2024;8(6):bvae090. Epub 2024/05/15. doi: 10.1210/jendso/bvae090. PubMed PMID: 38745825; PubMed Central PMCID: PMCPMC11091833.
61. Hangai M, Kawaguchi T, Takagi M, Matsuo K, Jeon S, Chiang CWK, Dewan AT, De Smith AJ, Imamura T, Okamoto Y, Saito AM, Deguchi T, Kubo M, Tanaka Y, Ayukawa Y, Hori T, Ohki K, Kiyokawa N, Inukai T, Arakawa Y, Mori M, Hasegawa D, Tomizawa D, Fukushima H, Yuza Y, Noguchi Y, Taneyama Y, Ota S, Goto H, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Nakamura K, Moriwaki K, Sekinaka Y, Morita D, Hirabayashi S, Hosoya Y, Yoshimoto Y, Yoshihara H, Ozawa M, Kobayashi S, Morisaki N, Gyeltshen T, Takahashi O, Okada Y, Matsuda M, Tanaka T, Inazawa J, Takita J, Ishida Y, Ohara A, Metayer C, Wiemels JL, Ma X, Mizutani S, Koh K, Momozawa Y, Horibe K, Matsuda F, Kato M, Manabe A, Urayama KY. Genome-wide assessment of genetic risk loci for childhood acute lymphoblastic leukemia in Japanese patients. Haematologica. 2024 Apr 1;109(4):1247-1252. doi: 10.3324/haematol.2023.282914. PMID: 37881853; PMCID: PMC10985430.
62. Ueki H, Ogawa C, Goto H, Nishi M, Yamanaka J, Mochizuki S, Nishikawa T, Kumamoto T, Nishiuchi R, Kikuta A, Yamamoto S, Igarashi S, Sato A, Hori T, Saito AM, Watanabe T, Deguchi T, Manabe A, Horibe K, Toyoda H. TBI, etoposide, and cyclophosphamide conditioning for intermediate-risk relapsed childhood acute lymphoblastic leukemia. Int J Hematol. 2024 Apr;119(4):450-458. doi: 10.1007/s12185-024-03710-6. Epub 2024 Jan 25. PMID: 38267673.
63. Wakisaka A, Kimura K, Morita H, Nakanishi K, Daimon M, Nojima M, Itoh H, Takeda A, Kitao R, Imai T, Ikeda T, Nakajima T, Watanabe C, Furukawa T, Ohno I, Ishida C, Takeda N, Komai K. Efficacy and Tolerability of Ivabradine for Cardiomyopathy in Patients with Duchenne Muscular Dystrophy. Int Heart J. 2024;65(2):211-217. doi: 10.1536/ihj.23-563. PMID: 38556332.
64. Segoe H, Nakamura A, Uetake K, Hishimura N, Kaneko N, Morikawa S, Nakamura-Utsunomiya A, Yamaguchi T. Adipsic hypernatremia with marked hyperprolactinemia and GH deficiency in a 9-year-old boy. Clin Pediatr Endocrinol. 2024;33(3):163-168. doi: 10.1297/cpe.2024-0001. Epub 2024 Apr 22. PMID: 38993721; PMCID: PMC11234189.
65. Saijo Y, Yoshioka E, Sato Y, Kunori Y, Kanaya T, Nakanishi K, Kato Y, Nagaya K, Takahashi S, Ito Y, Iwata H, Yamaguchi T, Miyashita C, Itoh S, Kishi R; Japan Environment and Children’s Study (JECS) Group. Maternal pre-pregnancy body mass index and related factors: A cross-sectional analysis from the Japan Environment and Children's Study. PLoS One. 2024 Jun 4;19(6):e0304844. doi: 10.1371/journal.pone.0304844. PMID: 38833493; PMCID: PMC11149848.
66. Nakanishi K, Mutoh M, Itoh S, Kobayashi S, Yamaguchi T, Iwata H, Tamura N, Koishi M, Kasai M, Kikuchi E, Yasuura N, Kishi R, Sato Y. Vitamin D concentration in maternal serum during pregnancy: Assessment in Hokkaido in adjunct study of the Japan Environment and Children's Study (JECS). PLoS One. 2024;19(11):e0312516. Epub 2024/11/15. doi: 10.1371/journal.pone.0312516. PubMed PMID: 39546451; PubMed Central PMCID: PMCPMC11567614.
67. Miyamoto S, Urayama KY, Arakawa Y, Koh K, Yuza Y, Hasegawa D, Taneyama Y, Noguchi Y, Yanagimachi M, Inukai T, Ota S, Takahashi H, Keino D, Toyama D, Takita J, Tomizawa D, Morio T, Koike K, Moriwaki K, Sato Y, Fujimura J, Morita D, Sekinaka Y, Nakamura K, Sakashita K, Goto H, Manabe A, Takagi M. Rare TCF3variants associated with pediatric B cell acute lymphoblastic leukemia. Pediatr Hematol Oncol. 2024;41(1):81-87. doi: 10.1080/08880018.2023.2201302. Epub 2023 May 2. PMID: 37129918.
68. Maruo Y, Shiraishi M, Hibino M, Abe J, Takeda A, Yamada Y. Activation of Mitochondria in Mesenchymal Stem Cells by Mitochondrial Delivery of Coenzyme Q(10). Biol Pharm Bull. 2024;47(8):1415-21. Epub 2024/08/08. doi: 10.1248/bpb.b24-00284. PubMed PMID: 39111843.
69. Iwata H, Ikeda A, Itoh M, Itoh S, Ketema RM, Tamura N, Miyashita C, Yamaguchi T, Yamazaki K, Yamamoto R, Tojo M, Saijo Y, Ito Y, Kishi R; Japan Environment and Children’s Study (JECS) Group. The association between flooring materials and childhood asthma: A prospective birth cohort in the Japan Environment and Children's Study. PLoS One. 2024 Jul 31;19(7):e0305957. doi: 10.1371/journal.pone.0305957. PMID: 39083507; PMCID: PMC11290634.
70. Ikeda A, Marsela M, Miyashita C, Yamaguchi T, Saijo Y, Ito Y, Iwata H, Itoh S, Itoh M, Yamazaki K, Tamura N, Kobayashi S, Kishi R; Japan Environment and Children’s Study Group. Heavy metals and trace elements in maternal blood and prevalence of congenital limb abnormalities among newborns: the Japan Environment and Children's Study. Environ Health Prev Med. 2024;29:36. doi: 10.1265/ehpm.23-00366. PMID: 39048352; PMCID: PMC11273044.
71. Saito R, Ozaki K, Baba Y, Ikegawa K, Nagasaki K, Nakamura A, Hamajima T, Higuchi S, Hasegawa Y. Adult Height in Girls with Central Precocious Puberty with Onset after 6 Years: Effects of Gonadotropin-Releasing Hormone Analog Therapy. Horm Res Paediatr. 2024 Nov 21:1-8. doi: 10.1159/000542038. Epub ahead of print. PMID: 39571550.
72. Abe J, Tsubaki J, Shimura K, Hasegawa T. A Pitfall of Adrenal Hypoplasia Congenita. Clin Pediatr (Phila). 2024 Oct;63(9):1318-1320. doi: 10.1177/00099228231222714. Epub 2024 Jan 27. PMID: 38279818; PMCID: PMC11373157.
73. Fujimoto M, Nakamura Y, Hosoki K, Iwaki T, Sato E, Ieda D, Hori I, Negishi Y, Hattori A, Shiraishi H, Saitoh S. Genotype-phenotype correlation over time in Angelman syndrome: Researching 134 patients. HGG Adv. 2024 Oct 10;5(4):100342. doi: 10.1016/j.xhgg.2024.100342. Epub 2024 Aug 22. PMID: 39169619; PMCID: PMC11404063.
74. Noguchi A, Tezuka T, Okuda H, Kobayashi H, Harada KH, Yoshida T, Akioka S, Wada K, Takeya A, Kabata-Murasawa R, Kondo D, Ishikawa K, Asano T, Fujiwara M, Hishikawa N, Mizukami T, Hitomi T, Youssefian S, Nagai Y, Tanaka M, Eto K, Shiraishi H, Amaya F, Koizumi A, Takahashi T. Genetic Analysis of SCN11A, SCN10A, and SCN9A in Familial Episodic Pain Syndrome (FEPS) in Japan and Proposal of Clinical Diagnostic Criteria. Int J Mol Sci. 2024 Jun 21;25(13):6832. doi: 10.3390/ijms25136832. PMID: 38999942; PMCID: PMC11241565.
75. Anada R, Watanabe H, Shimojo A, Shiraishi H, Yokosawa K. Brain activity supporting alternating speech for semantic words: simultaneous magnetoencephalographic recording. Cereb Cortex. 2024 Jan 31;34(2):bhae031. doi: 10.1093/cercor/bhae031. PMID: 38342686.

論文（邦文）

1. 岡本 孝之【小児臨床検査2024】腎・尿路系検査　尿細管機能検査　近位尿細管機能検査　尿細管リン再吸収閾値,重炭酸イオン負荷試験,尿中アミノ酸, 小児内科(0385-6305)56巻増刊 Page254-257(2024.10), DOI：10.24479/pm.0000001928
2. 森川 俊太郎【小児臨床検査2024】内分泌・代謝検査　性腺機能検査　テストステロン,ジヒドロテストステロン, 小児内科(0385-6305)56巻増刊 Page488-491(2024.10), DOI：10.24479/pm.0000001989
3. 安部 樹太朗【小児科学レビュー-最新主要文献とガイドライン-】血液疾患　造血器腫瘍, 小児科臨床(0021-518X)77巻5号 Page655-661(2024.10)
4. 長 祐子【知っておきたい子どもの痛み～予防法と痛みへのアプローチ～】大学病院における医療行為に伴う痛みの予防の実際, チャイルド ヘルス(1344-3151)27巻10号 Page754-757(2024.10), DOI：10.34433/ch.0000000646
5. 堀田 記世彦, 今 雅史, 千葉 博基, 広瀬 貴行, 樋口 まどか, 岩原 直也, 岡本 孝之, 篠原 信雄 小児慢性腎臓病における移行医療　泌尿器科医の役割, 日本小児腎不全学会雑誌(1341-5875)44巻 Page38-42(2024.08)
6. 植木 将弘, 岩井 一宏 OTULIN関連自己炎症症候群の分子病態, 臨床免疫・アレルギー科(1881-1930)82巻2号 Page188-198(2024.08)
7. 武田 充人 【公費補助制度を使いこなす!】総論　養育医療, 小児科診療(0386-9806)87巻8号 Page873-875(2024.08), DOI：10.34433/pp.0000001108
8. 平林 真介 【公費補助制度を使いこなす!】再生不良性貧血, 小児科診療(0386-9806)87巻8号 Page1050-1053(2024.08), DOI：10.34433/pp.0000001144
9. 兼次 洋介, 安積 陽子, 三谷 裕介, 水島 正人, 中川 真智子, 大石 芳久, 安達 裕行, 新井 浩和, 池田 尊司, 吉村 優子, 菊知 充, 長 和俊, 太田 英伸【小児科医が知っておくべき子どもの眠り】基礎疾患と睡眠障害　早産児・低出生体重児と睡眠障害, 小児内科(0385-6305)56巻8号 Page1279-1285(2024.08)
10. 平林 真介(北海道大学病院 小児科), 更科 岳大, 山本 雅樹, 小林 良二 非腫瘍性疾患に対する造血幹細胞移植　先天性免疫異常症の造血細胞移植　北海道地区から考える, 日本小児血液・がん学会雑誌(2187-011X)61巻2号 Page148-153(2024.07), DOI：10.11412/jspho.61.148
11. 山口 秀, 伊師 雪友, 茂木 洋晃, 寺下 友佳代, 平林 真介, 橋本 孝之, 真部 淳, 藤村 幹 小児血液腫瘍医療の集約化と均てん化　当院におけるキャンサーボードを中心とした小児脳腫瘍診療体制の構築, 日本小児血液・がん学会雑誌(2187-011X)61巻2号 Page154-158(2024.07), DOI：10.11412/jspho.61.154
12. 植木 将弘, 小林 一郎 【補体と腎疾患:温故知新】補体系の基本的な理解のために　補体欠損症と感染症, 腎と透析(0385-2156)97巻1号 Page45-49(2024.07), DOI：10.24479/kd.0000001391
13. 泉 岳 【植込み型心臓電気デバイス(Cardiac Implantable Electronic Devices:CIEDs)の進歩】先天性心疾患に対するCIEDs, 心臓(0586-4488)56巻6号 Page520-525(2024.06)
14. 岡本 孝之 【小児腎臓病学の進歩】コエンザイムQ10腎症, 日本腎臓学会誌(0385-2385)66巻3号 Page412-419(2024.05)
15. 真部 淳 小児がんの診療と研究　患児と家族を取り巻く様々な人たちの物語, 日本小児血液・がん学会雑誌(2187-011X)61巻1号 Page17-20(2024.05), DOI：10.11412/jspho.61.17
16. 泉 岳 小児・先天性心疾患の不整脈診療Up to Date　小児・先天性心疾患のデバイス治療, 日本小児循環器学会雑誌(0911-1794)40巻2号 Page113-120(2024.05)
17. 佐藤 泰征 【経過を追って考える　輸液の処方・調整のコツ　いつやめる?どう調整する?チェックするポイントとタイミングを押さえて、「何となく」の処方を見直そう】(第2章)病態・疾患ごとの輸液の処方・調整・終了　小児への輸液, レジデントノート(1344-6746)26巻2号 Page356-362(2024.04)
18. 武田 充人【完全把握をめざす小児の心疾患】後天性心疾患　小児の心筋症, 小児内科(0385-6305)56巻4号 Page657-660(2024.04), DOI：10.24479/pm.0000001632
19. 永井 礼子【完全把握をめざす小児の心疾患】後天性心疾患　肺高血圧症, 小児内科(0385-6305)56巻4号 Page667-670(2024.04), DOI：10.24479/pm.0000001634
20. 白石 秀明 近接領域学会の研究動向(第8回)　子どものてんかん, 子どもと発育発達(1348-3056)22巻1号 Page64-66(2024.04)
21. 長谷河 昌孝, 真部 淳【血液症候群(第3版)-その他の血液疾患を含めて-】その他　過粘稠度症候群, 日本臨床(0047-1852)別冊血液症候群V Page354-358(2024.03)
22. 平林 真介【造血不全症の診療】遺伝性骨髄不全症候群, 血液内科(2185-582X)88巻3号 Page271-276(2024.03)
23. 真部 淳 小児の輸血療法　小児の血液・がん診療における輸血療法, 日本産婦人科・新生児血液学会誌(0916-8796)33巻2号 Page43-46(2024.03)
24. 平林 真介【血液症候群(第3版)-その他の血液疾患を含めて-】骨髄系の腫瘍　骨髄異形成症候群　小児骨髄異形成症候群, 日本臨床(0047-1852)別冊血液症候群IV Page132-136(2024.02)
25. 佐藤 泰征【小児疾患におけるアフェレシス-治療法の1つの選択肢としての血液浄化療法-】各疾患に対するアフェレシス　感染症疾患に対するアフェレシス, 小児科診療(0386-9806)87巻1号 Page71-76(2024.01), DOI：10.34433/pp.0000000824
26. 小川 千登世, 石原 卓, 今井 千速, 岡本 康裕, 加藤 元博, 康 勝好, 後藤 裕明, 堺田 惠美子, 佐藤 篤, 下之段 秀美, 関水 匡大, 豊田 秀実, 早川 文彦, 矢野 未央, 山崎 悦子, 真部 淳 Consensus expert recommendations　本邦の実臨床での急性リンパ性白血病/リンパ芽球性リンパ腫(ALL/LBL)治療におけるアスパラギナーゼ製剤の最適使用の検討, 血液内科(2185-582X)88巻4号 Page445-454(2024.04)
27. 山口 秀, 伊師 雪友, 茂木 洋晃, 大木 聡悟, 寺下 友佳代, 長谷河 昌孝, 長 祐子, 平林 真介, 真部 淳, 藤村 幹 視路視床下部神経膠腫再発に対する化学療法を中心とした治療戦略, 小児の脳神経(0387-8023)49巻3号 Page81-87(2024.08), DOI：10.34544/jspn.49.3_81
28. 武田　充人『最新ガイドライン準拠 小児科診断・治療指針』改訂第３版　16章　循環器疾患　「心室中隔欠損症」 中山書店
29. 泉　岳 『最新ガイドライン準拠 小児科診断・治療指針』改訂第３版　16章　循環器疾患　「カテコラミン誘発多形性心室頻拍」 中山書店
30. 永井　礼子「房室中隔欠損（心内膜床欠損）」「動脈管開存症」「エプスタイン病」, 南江堂「最新の臨床WEB」
31. 武田　充人 小児・成育循環器学　改訂第2版 他の遺伝性心血管疾患「ミトコンドリア異常」
32. 植田佑樹「覚醒時，睡眠時の背景脳波活動の発達，加齢に伴う変化」 新版　どう読む？こう読む！てんかんの発作間欠期・発作時脳波（診断と治療社）
33. 江川潔「進行性ミオクローヌスてんかん（PME）」 新版　どう読む？こう読む！てんかんの発作間欠期・発作時脳波（診断と治療社）

令和5（2023）年度

2023年度研究費取得状況

論文・著書など

論文（欧文）

1. Abe J, Ueki M, Honjou R, Takeda K, Seto Y, Nakamura Y, Furuse Y, NakataK, Cho K. The clinical importance of pulmonary gene and proteinexpression levels in an infant with lethal ABCA3 variants. PediatrPulmonol. 2023 Oct;58(10):2956-2959. doi: 10.1002/ppul.26611. Epub 2023Jul 21. PMID: 37477506.
2. Arimitsu T, Fukutomi R, Kumagai M, Shibuma H, Yamanishi Y, TakahashiKI, Gima H, Seto Y, Adachi H, Arai H, HiguchiM, Ohgi S, Ohta H. Designing artificial circadian environments withmultisensory cares for supporting preterm infants' growth in NICUs.Front Neurosci. 2023 Aug 24;17:1152959. doi:10.3389/fnins.2023.1152959. PMID: 37694118; PMCID: PMC10491019.
3. Attarbaschi A, Möricke A, Harrison CJ, Mann G, Baruchel A, De MoerlooseB, Conter V, Devidas M, Elitzur S, Escherich G, Hunger SP, Horibe K,Manabe A, Loh ML, Pieters R, Schmiegelow K, Silverman LB, Stary J, VoraA, Pui CH, Schrappe M, Zimmermann M; Ponte-di-Legno Childhood AcuteLymphoblastic Leukemia Working Group. Outcomes of Childhood NoninfantAcute Lymphoblastic Leukemia With 11q23/ KMT2A Rearrangementsin a Modern Therapy Era: A Retrospective International Study. J ClinOncol. 2023 Mar 1;41(7):1404-1422. doi: 10.1200/JCO.22.01297. Epub 2022Oct 18. PMID: 36256911; PMCID: PMC9995095.
4. Chida-Nagai A, Masaki N, Maeda K, Sasaki K, Sato H, Muneuchi J, OchiaiY, Murayama H, Tahara M, Shiono A, Shinozuka A, Kono F, Machida D,Toyooka S, Sugimoto S, Nakamura K, Akagi S, Kondo M, Kasahara S, KotaniY, Koizumi J, Oda K, Harada M, Nakajima D, Murata A, Nagata H, YatsunamiK, Kobayashi T, Matsunaga Y, Inoue T, Yamagishi H, Nakagawa N, Ohtani K,Yamamoto M, Ito Y, Hokosaki T, Kuwahara Y, Masutani S, Nomura K, Wada T,Sawada H, Abiko M, Takahashi T, Ishikawa Y, Okada S, Naitoh A, Toda T,Ando T, Masuzawa A, Hoshino S, Kawada M, Nomura Y, Ueno K, Ohashi N,Tachibana T, Cao Y, Ueda H, Yanagi S, Koide M, Mitsushita N, Higashi K,Minosaki Y, Hayashi T, Okamoto T, Kuraishi K, Ehara E, Ishida H,Horigome H, Murakami T, Takei K, Ishii T, Harada G, Hirata Y, Maeda J,Tatebe S, Ota C, Hayabuchi Y, Sakazaki H, Sasaki T, Hirono K, Suzuki S,Yasuda M, Takeda A, Sawai M, Miyaji K, Kitagawa A, Nakai Y, Kakimoto N,Agematsu K, Manabe A, Saiki Y. Use of the index of pulmonary vasculardisease for predicting long-term outcome of pulmonary arterialhypertension associated with congenital heart disease. Front CardiovascMed. 2023 Sep 4;10:1212882. doi: 10.3389/fcvm.2023.1212882. Erratum in:Front Cardiovasc Med. 2024 Feb 01;11:1369831. PMID: 37731527; PMCID:PMC10507182.
5. Chida-Nagai A, Tonoki H, Makita N, Ishiyama H, Ihara M, Maruo Y,Tsujioka T, Sasaki D, Izumi G, Yamazawa H, Kato N, Ito M, Fujimura M,Sasaki O, Takeda A. A Noonan-like pediatric patient with a de novo CBLpathogenic variant and an RNF213 polymorphism p.R4810K presenting withcardiopulmonary arrest due to left main coronary artery ostial atresia.Am J Med Genet A. 2023 Dec;191(12):2837-2842. doi:10.1002/ajmg.a.63370. Epub 2023 Aug 9. PMID: 37554039.
6. Dong G, Adak S, Spyropoulos G, Zhang Q, Feng C, Yin L, Speck SL, ShyrZ, Morikawa S, Kitamura RA, Kathayat RS, Dickinson BC, Ng XW, PistonDW, Urano F, Remedi MS, Wei X, Semenkovich CF. Palmitoylation couplesinsulin hypersecretion with β cell failure in diabetes. Cell Metab.2023 Feb 7;35(2):332-344.e7. doi: 10.1016/j.cmet.2022.12.012. Epub 2023Jan 11. PMID: 36634673; PMCID: PMC9908855.
7. Egawa K, Watanabe M, Shiraishi H, Sato D, Takahashi Y, Nishio S, FukudaA. Imbalanced expression of cation-chloride cotransporters as apotential therapeutic target in an Angelman syndrome mouse model. SciRep. 2023 Apr 17;13(1):5685. doi: 10.1038/s41598-023-32376-z. PMID:37069177; PMCID: PMC10110603.
8. Eguchi K, Yaguchi H, Nakakubo S, Nakajima M, Ueda Y, Egawa K, ShiraishiH, Yabe I. Video-based detection of epileptic spasms in West syndromeusing a deep neural network: A pilot case study. J Neurol Sci. 2023 Jun15;449:120671. doi: 10.1016/j.jns.2023.120671. Epub 2023 May 5. PMID:37167655.
9. Elitzur S, Vora A, Burkhardt B, Inaba H, Attarbaschi A, Baruchel A,Escherich G, Gibson B, Liu HC, Loh M, Moorman AV, Möricke A, Pieters R,Uyttebroeck A, Baird S, Bartram J, Barzilai-Birenboim S, Batra S,Ben-Harosh M, Bertrand Y, Buitenkamp T, Caldwell K, Drut R, GeerlinksAV, Gilad G, Grainger J, Haouy S, Heaney N, Huang M, Ingham D, KrenovaZ, Kuhlen M, Lehrnbecher T, Manabe A, Niggli F, Paris C, Revel-Vilk S,Rohrlich P, Sinno MG, Szczepanski T, Tamesberger M, Warrier R, Wolfl M,Nirel R, Izraeli S, Borkhardt A, Schmiegelow K. EBV-driven lymphoidneoplasms associated with pediatric ALL maintenance therapy. Blood.2023 Feb 16;141(7):743-755. doi: 10.1182/blood.2022016975. PMID:36332176.
10. Fujishige S, Ogawa Y, Aoyagi H, Okamoto T. M-type phospholipase A2receptor-associated membranous nephropathy in a patient withNoonan-like syndrome with loose anagen hair. Pediatr Int. 2023Jan-Dec;65(1):e15643. doi: 10.1111/ped.15643. PMID: 37817399.
11. Fukuyama M, Horie M, Kato K, Aoki H, Fujita S, Yoshida Y, Sakazaki H,Toda T, Ueno M, Izumi G, Momoi N, Muneuchi J, Makiyama T, Nakagawa Y,Ohno S. Calmodulinopathy in Japanese Children　- Their CardiacPhenotypes Are Severe and Show Early Onset in Fetal Life and Infancy.Circ J. 2023 Nov 24;87(12):1828-1835. doi: 10.1253/circj.CJ-23-0195.Epub 2023 Jun 28. PMID: 37380439.
12. Hagio K, Kikuchi J, Takada K, Tanabe H, Sugiyama M, Ohhara Y, Amano T,Yuki S, Komatsu Y, Osawa T, Hatanaka KC, Hatanaka Y, Mitamura T, YabeI, Matsuno Y, Manabe A, Sakurai A, Ishiguro A, Takahashi M, Yokouchi H,Naruse H, Mizukami Y, Dosaka-Akita H, Kinoshita I. Assessment for thetiming of comprehensive genomic profiling tests in patients withadvanced solid cancers. Cancer Sci. 2023 Aug;114(8):3385-3395. doi:10.1111/cas.15837. Epub 2023 May 19. PMID: 37208840; PMCID: PMC10394138.
13. Hara-Isono K, Matsubara K, Nakamura A, Sano S, Inoue T, Kawashima S,Fuke T, Yamazawa K, Fukami M, Ogata T, Kagami M. Risk assessment ofassisted reproductive technology and parental age at childbirth for thedevelopment of uniparental disomy-mediated imprinting disorders causedby aneuploid gametes. Clin Epigenetics. 2023 May 6;15(1):78. doi:10.1186/s13148-023-01494-w. PMID: 37147716; PMCID: PMC10163687.
14. Hayashida K, Garcia A, Moonga LC, Sugi T, Takuya K, Kawase M, Kodama F,Nagasaka A, Ishiguro N, Takada A, Kajihara M, Nao N, Shingai M, Kida H,Suzuki Y, Hall WW, Sawa H, Yamagishi J. Field-deployable multiplexdetection method of SARS-CoV-2 and influenza virus using loop-mediatedisothermal amplification and DNA chromatography. PLoS One. 2023 May16;18(5):e0285861. doi: 10.1371/journal.pone.0285861. PMID: 37192155;PMCID: PMC10187927.
15. Hoshino Y, Arai J, Cho K, Yukitake Y, Kajikawa D, Hinata A, Miura R.Diagnosis and management of neonatal respiratory distress syndrome inJapan: A national survey. Pediatr Neonatol. 2023 Jan;64(1):61-67. doi:10.1016/j.pedneo.2022.08.002. Epub 2022 Aug 28. PMID: 36089536.
16. Hosokawa C, Hotta K, Okamoto T, Cho Y, Hirose T, Iwahara N, Manabe A,Shinohara N. Prophylactic bilateral nephrectomy and preemptive kidneytransplantation for Denys-Drash syndrome prior to development of kidneyfailure. Pediatr Nephrol. 2024 Mar;39(3):905-909. doi:10.1007/s00467-023-06113-7. Epub 2023 Aug 12. PMID: 37572117.
17. Imai C, Sato A, Hiwatari M, Shimomura Y, Hori T, Suenobu S, Imamura T,Hara J, Hasegawa D, Takahashi H, Moriya K, Katayama S, Tomizawa D,Moritake H, Taga T, Horibe K, Koh K, Manabe A, Okamoto Y. Outcomesfollowing induction failure in Japanese children with acutelymphoblastic leukemia. Int J Hematol. 2023 Jul;118(1):99-106. doi:10.1007/s12185-023-03600-3. Epub 2023 Apr 10. PMID: 37037958.
18. Iwahata Y, Takae S, Iwahata H, Matsumoto K, Hirayama M, Takita J,Manabe A, Cho Y, Ikeda T, Maezawa T, Miyachi M, Keino D, Koizumi T,Mori T, Shimizu N, Woodruff TK, Suzuki N. Investigation of FertilityPreservation Education Videos for Pediatric Patients Based onInternational and Historical Survey. J Adolesc Young Adult Oncol. 2023Dec;12(6):835-842. doi: 10.1089/jayao.2022.0154. Epub 2023 May 8. PMID:37155199.
19. Iwasaki S, Sato R, Kagami K, Akizawa K, Hayasaka K, Fukumoto T, Taki K,Niinuma Y, Yamada T, Oyamada R, Watanabe T, Nakakubo S, Watanabe C,Teshima T, Ishiguro N. Breaking away from an endemic state ofmultidrug-resistant Pseudomonas aeruginosa by daily sinkdisinfection. Antimicrob Steward Healthc Epidemiol. 2023 Nov15;3(1):e209. doi: 10.1017/ash.2023.484. PMID: 38156227; PMCID:PMC10753494.
20. Izumi G, Takeda A, Okamoto T, Shida S, Matsuo H. A case oftachycardia-induced acute kidney injury by renal hypouricemia. JCardiol Cases. 2023 Nov 10;29(2):59-62. doi:10.1016/j.jccase.2023.10.009. PMID: 38362583; PMCID: PMC10865112.
21. Kagami K, Ishiguro N, Iwasaki S, Usami T, Fukumoto T, Hayasaka K,Oyamada R, Watanabe T, Nakakubo S, Niinuma Y, Hagino T, Abe Y, FujimotoI, Maekawa H, Fujibayashi R, Fuke S, Asahi K, Ota S, Nagakura T, OkuboT, Asanuma H, Ito T, Okano S, Komatsu E, Sasaki K, Hashimoto K, WashiyaK, Kato Y, Kusumi K, Asai Y, Saito Y, Sakai Y, Sakurada M, Sakimoto Y,Ichikawa Y, Kinebuchi T, Kondo D, Kanno S, Kobayashi M, Hirabayashi K,Saitou S, Saito K, Ebina Y, Koshizaki Y, Chiba M, Yasuda A, Sato T,Togashi A, Abe T, Fujita T, Umehara K, Amishima M, Murakami N, Yagi T,Fujimoto S, Tajima T, Sugawara M, Takekuma Y. Correlation betweenantibiotic use and antibiotic resistance: A multicenter study using theJapan Surveillance for Infection Prevention and Healthcare Epidemiology(J-SIPHE) system in Hokkaido, Japan. Am J Infect Control. 2023Feb;51(2):163-171. doi: 10.1016/j.ajic.2022.05.025. Epub 2022 Jun 5.PMID: 35671846.
22. Kagami K, Ishiguro N, Iwasaki S, Taki K, Fukumoto T, Hayasaka K,Oyamada R, Watanabe T, Nakakubo S, Niinuma Y, Sugawara M, Takekuma Y.Correlation between antibiotic use and resistance of gram-negativebacteria at a university hospital in Japan from 2013 to 2021: a studyusing the Japan Surveillance for Infection Prevention and HealthcareEpidemiology (J-SIPHE) system. Eur J Hosp Pharm. 2023 Jul12:ejhpharm-2023-003797. doi: 10.1136/ejhpharm-2023-003797. Epub aheadof print. PMID: 37438092.
23. Kagami K, Kitajima M, Takahashi H, Teshima T, Ishiguro N. Associationof wastewater SARS-CoV-2 load with confirmed COVID-19 cases at auniversity hospital in Sapporo, Japan during the period from February2021 to February 2023. Sci Total Environ. 2023 Nov 15;899:165457. doi:10.1016/j.scitotenv.2023.165457. Epub 2023 Jul 25. PMID: 37499823.
24. Kagami K, Oyamada R, Watanabe T, Nakakubo S, Hayashi T, Iwasaki S,Fukumoto T, Usami T, Hayasaka K, Fujisawa S, Watanabe C, Nishida M,Teshima T, Niinuma Y, Yokota I, Takekuma Y, Sugawara M, Ishiguro N.Factors associated with household transmission of SARS-CoV-2 omicronvariant to health care workers: A retrospective cohort study. Int JNurs Pract. 2023 Oct;29(5):e13195. doi: 10.1111/ijn.13195. Epub 2023Aug 24. PMID: 37621085.
25. Kawaguchi K, Umeda K, Miyamoto S, Yoshida N, Yabe H, Koike T, KajiwaraM, Kawaguchi H, Takahashi Y, Ishimura M, Sakaguchi H, Hama A, Cho Y,Sato M, Kato K, Sato A, Kato K, Tabuchi K, Atsuta Y, Imai K.Graft-versus-host disease-free, relapse-free, second transplant-freesurvival in allogeneic hematopoietic cell transplantation for geneticdisorders. Bone Marrow Transplant. 2023 May;58(5):600-602. doi:10.1038/s41409-023-01937-1. Epub 2023 Feb 16. PMID: 36797422.
26. Kenri T, Yamazaki T, Ohya H, Jinnai M, Oda Y, Asai S, Sato R, IshiguroN, Oishi T, Horino A, Fujii H, Hashimoto T, Nakajima H, Shibayama K.Genotyping of Mycoplasma pneumoniae strains isolated in Japanduring 2019 and 2020: spread of p1 gene type 2c and 2j variantstrains. Front Microbiol. 2023 Jun 19;14:1202357. doi:10.3389/fmicb.2023.1202357. PMID: 37405159; PMCID: PMC10316025.
27. Kudo H, Suzuki R, Kondo A, Nozu K, Nakamura Y, Mikami H, Soma J, NakayaI. Association of Familial Fanconi Syndrome with a Novel GATM Variant.Tohoku J Exp Med. 2023 Aug 23;260(4):337-340. doi:10.1620/tjem.2023.J046. Epub 2023 Jun 8. PMID: 37286521.
28. Maezawa T, Suzuki N, Takeuchi H, Nishioka M, Hidaka M, Manabe A, KogaY, Kawaguchi H, Sasahara Y, Tachibana M, Iwamoto S, Horie A, HiramatsuH, Kato M, Harada M, Yuza Y, Hirayama M, Takita J, Ikeda T, MatsumotoK. Challenges to Widespread Use of Fertility Preservation Facilitiesfor Pediatric Cancer Patients in Japan. J Adolesc Young Adult Oncol.2023 Aug 3. doi: 10.1089/jayao.2023.0059. Epub ahead of print. PMID:37535825.
29. Maruo Y, Saito Y, Nishino I, Takeda A. Successful treatment of frequentpremature ventricular contractions and non-sustained ventriculartachycardia with verapamil and flecainide in RYR1-relatedmyopathy: a case report. Eur Heart J Case Rep. 2023 Oct13;7(10):ytad509. doi: 10.1093/ehjcr/ytad509. PMID: 37881357; PMCID:PMC10597318.
30. Miura K, Hattori M, Iwano M, Inoue E, Gotoh Y, Okamoto T, Nishiyama K,Hirano D, Nishimura K, Narita I. Depression and health-related qualityof life in adolescents and young adults with childhood-onset end-stagekidney disease: a multicenter study in Japan. Clin Exp Nephrol. 2023May;27(5):473-479. doi: 10.1007/s10157-023-02330-4. Epub 2023 Feb 25.PMID: 36840901.
31. Miura K, Hattori M, Iwano M, Okamoto T, Hamasaki Y, Gotoh Y, NishiyamaK, Fujinaga S, Hisano M, Hirano D, Narita I. Medical and psychosocialoutcomes in adolescents and young adults with childhood-onset end-stagekidney disease: a multicenter study in Japan. Clin Exp Nephrol. 2023May;27(5):454-464. doi: 10.1007/s10157-023-02327-z. Epub 2023 Feb 18.PMID: 36808382.
32. Nagasaki K, Minamitani K, Nakamura A, Kobayashi H, Numakura C, Itoh M,Mushimoto Y, Fujikura K, Fukushi M, Tajima T. Guidelines for NewbornScreening of Congenital Hypothyroidism (2021 Revision). Clin PediatrEndocrinol. 2023;32(1):26-51. doi: 10.1297/cpe.2022-0063. Epub 2022 Dec4. PMID: 36761493; PMCID: PMC9887297.
33. Nakakubo S, Hiramatsu Y, Goto T, Kimura S, Narugami M, Nakajima M, UedaY, Shiraishi H, Manabe A, Sharmin D, Cook JM, Egawa K. Therapeuticeffects of KRM-II-81, positive allosteric modulator for α2/3 subunitcontaining GABA_Areceptors, in a mouse model of Dravetsyndrome. Front Pharmacol. 2023 Oct 2;14:1273633. doi:10.3389/fphar.2023.1273633. PMID: 37849734; PMCID: PMC10577232.
34. Nakamura Y, Kobayashi S, Cho K, Itoh S, Miyashita C, Yamaguchi T, IwataH, Tamura N, Saijo Y, Ito Y, Seto Y, Honjo R, Ando A, Furuse Y, ManabeA, Kishi R; Japan Environment and Children’s Study (JECS) Group.Prenatal metal concentrations and physical abnormalities in the JapanEnvironment and Children's Study. Pediatr Res. 2023 Oct 19. doi:10.1038/s41390-023-02851-4. Epub ahead of print. Erratum in: PediatrRes. 2024 Mar 8;: PMID: 37857850.
35. Nishimura A, Yokoyama K, Naruto T, Yamagishi C, Imamura T, Nakazono H,Kimura S, Ito M, Sagisaka M, Tanaka Y, Piao J, Namikawa Y, YanagimachiM, Isoda T, Kanai A, Matsui H, Isobe T, Sato-Otsubo A, Higuchi N,Takada A, Okuno H, Saito S, Karakawa S, Kobayashi S, Hasegawa D,Fujisaki H, Hasegawa D, Koike K, Koike T, Rai S, Umeda K, Sano H,Sekinaka Y, Ogawa A, Kinoshita A, Shiba N, Miki M, Kimura F, NakayamaH, Nakazawa Y, Taga T, Taki T, Adachi S, Manabe A, Koh K, Ishida Y,Takita J, Ishikawa F, Goto H, Morio T, Mizutani S, Tojo A, Takagi M.Myeloid/natural killer (NK) cell precursor acute leukemia as a distinctleukemia type. Sci Adv. 2023 Dec 15;9(50):eadj4407. doi:10.1126/sciadv.adj4407. Epub 2023 Dec 13. PMID: 38091391.
36. Ohki K, Butler ER, Kiyokawa N, Hirabayashi S, Bergmann AK, Möricke A,Boer JM, Cavé H, Cazzaniga G, Yeoh AEJ, Sanada M, Imamura T, Inaba H,Mullighan CG, Loh ML, Norén-Nyström U, Shih LY, Zaliova M, Pui CH, HaasOA, Harrison CJ, Moorman AV, Manabe A. Clinical characteristics andoutcomes of B-cell precursor ALL with MEF2D rearrangements: aretrospective study by the Ponte di Legno Childhood ALL Working Group.Leukemia. 2023 Jan;37(1):212-216. doi: 10.1038/s41375-022-01737-4. Epub2022 Oct 29. PMID: 36309560; PMCID: PMC9883149.
37. Okada E, Aoto Y, Horinouchi T, Yamamura T, Ichikawa Y, Tanaka Y, UedaC, Kitakado H, Kondo A, Sakakibara N, Suzuki R, Usui J, Yamagata K,Iijima K, Nozu K. Aberrant splicing caused by exonic single nucleotidevariants positioned 2nd or 3rd to the last nucleotide in the COL4A5gene. Clin Exp Nephrol. 2023 Mar;27(3):218-226. doi:10.1007/s10157-022-02294-x. Epub 2022 Nov 12. PMID: 36371577; PMCID:PMC9950164.
38. Okada E, Horinouchi T, Yamamura T, Aoto Y, Suzuki R, Ichikawa Y, TanakaY, Masuda C, Kitakado H, Kondo A, Sakakibara N, Ishiko S, Nagano C,Ishimori S, Usui J, Yamagata K, Matsuo M, Nozu K. All reportednon-canonical splice site variants in GLA cause aberrant splicing. ClinExp Nephrol. 2023 Sep;27(9):737-746. doi: 10.1007/s10157-023-02361-x.Epub 2023 May 31. PMID: 37254000; PMCID: PMC10432374.
39. Onodera M, Uchiyama T, Ariga T, Yamada M, Miyamura T, Arizono H, MorioT. Safety and efficacy of elapegademase in patients with adenosinedeaminase deficiency: A multicenter, open-label, single-arm, phase 3,and postmarketing clinical study. Immun Inflamm Dis. 2023Jul;11(7):e917. doi: 10.1002/iid3.917. PMID: 37506145; PMCID:PMC10367445.
40. Ozono S, Sakashita K, Yoshida N, Kakuda H, Watanabe K, Maeda M, IshidaY, Manabe A, Taga T, Muramatsu H. A nationwide survey of late effectsin survivors of juvenile myelomonocytic leukemia in Japan. PediatrBlood Cancer. 2023 Feb;70(2):e30126. doi: 10.1002/pbc.30126. Epub 2022Dec 10. PMID: 36495260.
41. Sakashita K, Yoshida N, Muramatsu H, Ohtsuka Y, Watanabe K, Yabe M,Kakuda H, Honda Y, Watanabe T, Haba M, Ohmori S, Matsuda K, Yuza Y,Saito A, Horibe K, Adachi S, Manabe A. Allogeneic Hematopoietic CellTransplantation for Juvenile Myelomonocytic Leukemia with a Busulfan,Fludarabine, and Melphalan Regimen: JPLSG JMML-11. Transplant CellTher. 2024 Jan;30(1):105.e1-105.e10. doi: 10.1016/j.jtct.2023.10.002.Epub 2023 Oct 7. PMID: 37806448.
42. Sato A, Hatta Y, Imai C, Oshima K, Okamoto Y, Deguchi T, Hashii Y,Fukushima T, Hori T, Kiyokawa N, Kato M, Saito S, Anami K, Sakamoto T,Kosaka Y, Suenobu S, Imamura T, Kada A, Saito AM, Manabe A, Kiyoi H,Matsumura I, Koh K, Watanabe A, Miyazaki Y, Horibe K. Nelarabine,intensive L-asparaginase, and protracted intrathecal therapy for newlydiagnosed T-cell acute lymphoblastic leukaemia in children and youngadults (ALL-T11): a nationwide, multicenter, phase 2 trial includingrandomisation in the very high-risk group. Lancet Haematol. 2023Jun;10(6):e419-e432. doi: 10.1016/S2352-3026(23)00072-8. Epub 2023 May8. Erratum in: Lancet Haematol. 2023 Jun;10(6):e399. PMID: 37167992.
43. Sato H, Inoue Y, Kawashima Y, Konno R, Ohara O, Kuwana M, Kobayashi N,Takezaki S, Akioka S. In-depth proteomic analysis of juveniledermatomyositis serum reveals protein expression associated withmuscle-specific autoantibodies. Rheumatology (Oxford). 2023 Oct3;62(10):3501-3506. doi: 10.1093/rheumatology/kead165. PMID: 37052527.
44. Sato I, Takeda A. Long-term survival case with severe infantile Marfansyndrome: A case report. Pediatr Int. 2023 Jan-Dec;65(1):e15571. doi:10.1111/ped.15571. PMID: 37459280.
45. Shiraishi H, Egawa K, Murakami K, Nakajima M, Ueda Y, Nakakubo S,Narugami M, Kimura S, Goto T, Hiramatsu Y, Murakami M. Transcutaneousauricular vagus nerve stimulation therapy in patients with cognitivelypreserved structural focal epilepsy: A case series report. Brain Dev.2024 Jan;46(1):49-56. doi: 10.1016/j.braindev.2023.08.007. Epub 2023 Aug30. PMID: 37657962.
46. Shiraishi H, Teramoto T, Yokoshiki S, Tohyama J, Ueda Y, Egawa K, SatoN, Manabe A, Kato M. Efficacy of sirolimus for epileptic seizures inchildhood associated with focal cortical dysplasia type II. Brain Dev.2023 Jun;45(6):343-347. doi: 10.1016/j.braindev.2023.02.005. Epub 2023Mar 2. PMID: 36870920.
47. Suzuki R, Sakakibara N, Ichikawa Y, Kitakado H, Ueda C, Tanaka Y, OkadaE, Kondo A, Ishiko S, Ishimori S, Nagano C, Yamamura T, Horinouchi T,Okamoto T, Nozu K. Systematic Review of Clinical Characteristics andGenotype-Phenotype Correlation in LAMB2-Associated Disease.Kidney Int Rep. 2023 Jul 4;8(9):1811-1821. doi:10.1016/j.ekir.2023.06.019. PMID: 37705905; PMCID: PMC10496080.
48. Takeda A, Ueki M, Abe J, Maeta K, Horiguchi T, Yamazawa H, Izumi G,Chida-Nagai A, Sasaki D, Tsujioka T, Sato I, Shiraishi M, Matsuo M. Acase of infantile Barth syndrome with severe heart failure: Importanceof splicing variants in the TAZ gene. Mol Genet Genomic Med. 2023Jul;11(7):e2190. doi: 10.1002/mgg3.2190. Epub 2023 Apr 25. PMID:37186429; PMCID: PMC10337275.
49. Ueda Y, Egawa K, Kawamura K, Ochi N, Goto T, Kimura S, Narugami M,Nakakubo S, Nakajima M, Manabe A, Shiraishi H. Nusinersen inducesdetectable changes in compound motor action potential response inspinal muscular atrophy type 1 patients with severe impairment of motorfunction. Brain Dev. 2024 Mar;46(3):149-153. doi:10.1016/j.braindev.2023.12.001. Epub 2023 Dec 15. PMID: 38103972.
50. Ueda Y, Furugen A, Kobayashi M, Sato Y, Ueda Y, Hayashi A, Goto T,Kimura S, Narugami M, Nakakubo S, Nakajima M, Egawa K, Okamoto T,Manabe A, Shiraishi H. Use of lacosamide for focal epilepsy in a childwith kidney failure undergoing peritoneal dialysis. Brain Dev. 2024Feb;46(2):114-117. doi: 10.1016/j.braindev.2023.10.003. Epub 2023 Oct31. PMID: 37914622.
51. Ueda Y, Okamoto T, Sato Y, Hayashi A, Takahashi T, Suzuki R, Aoyagi H,Ueno M, Kobayashi N, Uetake K, Nakanishi M, Ariga T, Manabe A. Changesin bone turnover markers after discontinuing long-term glucocorticoidadministration in children with idiopathic nephrotic syndrome: amulticenter retrospective observational study. Pediatr Nephrol. 2023Oct;38(10):3285-3296. doi: 10.1007/s00467-023-05966-2. Epub 2023 Apr 13.PMID: 37052692.
52. Ueki M, Sakamoto K, Nishioka N, Ohata H, Nobuta T, Takezaki S, ManabeA, Yamada M. Rheumatologic manifestations with elevated levels of IL-6,IL-17A, and IL-23 in a patient with scurvy. Mod Rheumatol Case Rep.2023 Jan 3;7(1):302-306. doi: 10.1093/mrcr/rxac059. PMID: 35942728.
53. Yamada M, Suzuki H, Miya F, Kosugiyama K, Ujiie T, Tonoki H, Kosaki K.Precise definition of the breakpoints of an apparently balancedtranslocation between chromosome 3q26 and chromosome 7q36: Role ofKMT2C disruption. Congenit Anom (Kyoto). 2023 Jul;63(4):121-124. doi:10.1111/cga.12514. Epub 2023 Mar 28. PMID: 36946065.
54. Yamaguchi A, Tazawa Y, Ueki M, Yamada M, Manabe A, Sugawara M, TakekumaY. Therapeutic Drug Monitoring of Oral Voriconazole in an Infant Lessthan Six Months of Age and Pharmacokinetics Changes Induced byDevelopment of CYP2C19 in the Growth Process: A Novel Case Report.Yakugaku Zasshi. 2023;143(6):545-549. doi: 10.1248/yakushi.23-00001.PMID: 37258188.
55. Yoshida M, Nakabayashi K, Yang W, Sato-Otsubo A, Tsujimoto SI,Ogata-Kawata H, Kawai T, Ishiwata K, Sakamoto M, Okamura K, Yoshida K,Shirai R, Osumi T, Kiyotani C, Shioda Y, Terashima K, Ishimaru S, YuzaY, Takagi M, Arakawa Y, Imamura T, Hasegawa D, Inoue A, Yoshioka T, ItoS, Tomizawa D, Koh K, Matsumoto K, Kiyokawa N, Ogawa S, Manabe A, NiwaA, Hata K, Yang JJ, Kato M. Prevalence of pathogenic variants incancer-predisposing genes in second cancer after childhood solidcancers. Cancer Med. 2023 May;12(10):11264-11273. doi:10.1002/cam4.5835. Epub 2023 Apr 6. PMID: 37021926; PMCID: PMC10242325.
56. Zhao J, Ueki M, Sawai S, Sugiyama M, Terashita Y, Hirabayashi S, Cho Y,Kobayashi R, Tanaka Y, Manabe A. The heterozygous NUDT15 variant is notassociated with the severity of 6-mercaptopurine-related side effectsin early intensification therapy for childhood acute lymphoblasticleukemia. EJC Paediatric Oncology, Volume 1, 100006.https://doi.org/10.1016/j.ejcped.2023.100006

論文（邦文）

1. 鈴木諒太、野津寛大: X染色体の不活化と遺伝性腎疾患. 腎と透析94(3): 460-465, 2023
2. 武田充人：ミトコンドリア病における全身麻酔と鎮静. 「ミトコンドリア病診療マニュアル2023」（診断と治療社,2023）
3. 武田充人：ミトコンドリア心筋症を中心にした代謝と病態の関連. 生体の科学「代謝」Vol.74 No.5, 2023
4. 武田充人：ミトコンドリア心筋症. 日本臨床　2023年11月号
5. 武田充人：デュシェンヌ型筋ジストロフィー（DMD)診療の最前線　合併症のケア「心筋症の管理」. Progress in medicine　2023年11月号
6. 武田充人: 救急外来で見つけて対応するー時間的余裕のない場合「心筋障害,心不全」.小児科ベストプラクティス　外来で見つける先天代謝異常症ーシマウマ診断の勧め（中山書店, 　2023）
7. 武田 充人、山澤 弘州、池田 善彦：CQ17 ミトコンドリア心筋症の診断の進め方は？.「ミトコンドリア病診療マニュアル2023」（診断と治療社,2023）
8. 武田 充人、岡崎 敦子：CQ16 ミトコンドリア心筋症の症状は？. 「ミトコンドリア病診療マニュアル2023」（診断と治療社,2023）
9. 武田 充人、岡崎 敦子：CQ15 ミトコンドリア心筋症とはどのような疾患ですか？.「ミトコンドリア病診療マニュアル2023」（診断と治療社,2023）
10. 菱村希：こどものことをもっと知ろう 低身長. LiSA Vol.30 No.12, 2023
11. 竹崎俊一郎：感染症の予防や注意点に関するQ＆A. 「若年性特発性関節炎患者支援の手引き」（羊土社, 2023）
12. 竹崎俊一郎：感染症の予防や注意点に関するQ&A.「若年性特発性関節炎患者支援の手引き」
13. 竹崎俊一郎：CQ7　小児喘息患者において、吸入ステロイド薬(ICS)で長期管理中にステップアップする際はICSの増量とICSに長時間作用性吸入β2刺激薬(LABA)を追加する方法(ICS/LABA)のどちらが有用か？.「小児気管支喘息治療・管理ガイドライン2023」
14. 竹崎俊一郎：CQ4　小児喘息患者の長期管理において、有症状時にのみ吸入ステロイド薬(ICS)を吸入（間欠吸入）することは有用か？.「小児気管支喘息治療・管理ガイドライン2023」
15. 竹崎俊一郎：CQ2　小児喘息思者の長期管理において、ダニアレルゲン特異的免疫療法は有用か？. 「小児気管支喘息治療・管理ガイドライン2023」
16. 竹崎俊一郎：CQ13　小児のウイルス感染による喘鳴の治療にロイコトリエン受容体拮抗薬(LTRA)は有用か？.「小児気管支喘息治療・管理ガイドライン2023」
17. 泉岳：CQ 20　ミトコンドリア心筋症に合併する不整脈とその治療は？. 「ミトコンドリア病診療マニュアル2023」（診断と治療社,2023）
18. 岡本孝之：病因・病態生理から読み解く腎・泌尿器疾患のすべて「TINU症候群（サルコイドーシス）」. 腎と透析 2023年95巻増刊号
19. 岡本孝之：エキスパートが教える小児の薬物治療「腎性尿崩症」.小児内科 2023年55巻増刊号
20. 永井礼子：肺高血圧症の遺伝学的背景に関する最近の話題. 日本小児循環器学会雑誌　2023; 39(2): 62‒68
21. 植田佑樹： CQ1 発作が遷延する場合の早期治療にはどのようなものがあるか.「小児てんかん重積状態・けいれん重積状態治療ガイドライン」（診断と治療社, 2023）
22. 真部淳：小児の骨髄異形成症候群. 血液専門医テキスト（改訂第4版）（日本血液学会編）、p459-462, 2023、南江堂（東京）
23. 真部淳：チーム医療における保育士の役割　–小児がんを例にとって–. 医療と保育 21:2-10, 2023
24. 齋藤昭彦、伊藤秀一、成田雅美、齋藤伸治、大賀正一、真部淳：新型コロナウイルス感染症による大学病院の面会・付き添い制限の現状と課題. 日児誌　127:1540-1545,2023
25. 真部淳：がん・白血病の病名告知をめぐる課題. 小児科 64:577-582,2023
26. 寺下友佳代、真部淳：移行期医療. がん・生殖医療 （柴原浩章編集、鈴木直企画）、p178-180, 2023、中外医学社（東京）
27. 真部淳、長谷川大輔、多賀崇、小島勢二：Congenital dyserythropoietic anemia　(CDA)　遺伝性骨髄不全症診療ガイドライン2023（日本小児血液・がん学会編）診断と治療社（東京）2023 p37-43, 2023
28. 平林真介、真部淳、大木健太郎、清河信敬：小児B前駆細胞性急性リンパ性白血病におけるZNF384再構成とMEF2D再構成の特徴. 臨床血液　64:633-638,2023
29. 三田村真太郎, 石川耕資, 長和俊, 古瀬優太, 中村雄一, 本庄遼太, 前田拓, 山本有平.低出生体重児の顔面に生じた乳児血管腫に対するプロプラノロール内服療法の2例. 形成外科 66巻11号　Page1336-1345(2023.11)
30. 小野夏実, 金子直哉, 中山加奈子, 菱村希, 山口健史, 森川俊太郎, 真部淳,中村明枝：高用量ステロイド吸入により医原性グルココルチコイド過剰および二次性副腎皮質機能不全をきたした女児例. 臨床小児医学 70(1-6):57-63, 2023

特許

特許　第7218897号, 出願番号　特願 2018-551676
心不全の治療及び/又は予防に用いるための心筋幹細胞の製造方法
（発明者　原島秀吉、山田勇磨、阿部二郎、武田充人）

令和4（2022）年度

2022年度研究費取得状況

論文・著書など

論文（欧文）

1. Takizawa K, Ueda K, Sekiguchi M, Nakano E, Kajiho Y, Kanda S, Miura K, Hattori M, Hashimoto J, Hamasaki Y, Hisano M, Omori T, Okamoto T, Kitayama H, Fujita N, Kuramochi H, Ichiki T, Oka A, Harita Y: Urinary extracellular vesicles signature for diagnosis of kidney disease. iScience. 25(11): 105416, 2022
2. Nagano C, Hara S, Yoshikawa N, Takeda A, Gotoh Y, Hamada R, Matsuoka K, Yamamoto M, Fijinaga S, Sakuraya K, Kamei K, Hamasaki Y, Oguchi H, Araki Y, Ogawa Y, Okamoto T, Ito S, Tanaka S, Kaito H, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Horinouchi T, Yamamura T, Nagase H, Iijima K, Nozu K: Clinical, pathological and genetic characteristics in patients with focal segmental glomerulosclerosis. Kidney360 3(8):　1384-1393, 2022
3. Hayashi A, Okamoto T, Nio-Kobayashi J, Iwahara N, Suzuki R, Ueda Y, Takahashi T, Sato Y, Iwanaga T, Hotta K: CD44 as a pathological marker for early detection of calcineurin inhibitor-induced nephrotoxicity after kidney transplantation. Biomed Res 43(5): 181-186, 2022
4. Takahashi T, Okamoto T, Yokota I, Sato Y, Hayashi A, Ueda Y, Aoyagi H, Ueno M, Kobayashi N, Uetake K, Nakanishi M, Ariga T. The effect of rituximab on the quality of life of children with refractory nephrotic syndrome. Pediatr Int 64(1), 2022
5. Iijima K, Sako M, Oba M, Tanaka S, Hamada R, Sakai T, Ohwada Y, Ninchoji T, Yamamura T, Machida H, Shima Y, Tanaka R, Kaito H, Araki Y, Morohashi T, Kumagai N, Gotoh Y, Ikezumi Y, Kubota T, Kamei K, Fujita N, Ohtsuka Y, Okamoto T, Yamada T, Tanaka E, Shimizu M, Horinochi T, Konishi A, Omori T, Nakanishi K, Ishikura K, Ito S, Nakamura H, Nozu K; Japanese Study Group of Kidney Disease in Children. Mycophenolate Mofetil after Rituximab for Childhood-Onset Complicated Frequently-Relapsing or Steroid-Dependent Nephrotic Syndrome. J Am Soc Nephrol. 33(2):401-419, 2022
6. Ueda Y, Okamoto T, Sato Y, Hayashi A, Takahashi T, Kamada K, Honda S, Hotta K. Kidney transplantation after peritoneal dialysis-associated peritonitis and abdominal abscesses caused by Mycobacterium massiliense: lesson for the clinical nephrologist. J Nephrol 35(7), 2022
7. Suzuki R, Hayashi A, Endo M, Ueda Y, Takahashi T, Sato Y, Okamoto T. Cooccurrence of Alport syndrome and poststreptococcal acute glomerulonephritis with improvement after steroid administration. CEN Case Rep 11(4), 2022
8. Morikawa S, Urano F: The Role of ER Stress in Diabetes: Exploring Pathological Mechanisms Using Wolfram Syndrome. Int J Mol Sci 24(1): 230, 2022
9. Morikawa S, Blacher, Onwumere C, Urano F: Loss of function of WFS1 causes ER stress-mediated inflammation in pancreatic beta-cells. Front Endocrinol 13, 2022
10. Batjargal K, Tajima T, Fujita-Jimbo E, Yamaguchi T, Nakamura A, Yamagata T: Functional analysis of PAX8 variants identified in patients with congenital hypothyroidism in situ. Clin Pediatr Endocrinol 31(4): 234-241, 2022
11. Kobayashi S, Itoh S, Miyashita C, Ait Bamai Y, Yamaguchi T, Masuda H, Itoh M, Yamazaki K, Tamura N, Hanley SJB, Ikeda-Araki A, Saijo Y, Ito Y, Iwai-Shimada M, Yamazaki S, Kamijima M, Kishi R; Japan Environment, Children's Study JECS Group: Impact of prenatal exposure to mercury and selenium on neurodevelopmental delay in children in the Japan environment and Children's study using the ASQ-3 questionnaire: A prospective birth cohort. Environ Int 168, 2022
12. Itoh S, Yamazaki K, Suyama S, Ikeda-Araki A, Miyashita C, Ait Bamai Y, Kobayashi S, Masuda H, Yamaguchi T, Goudarzi H, Okada E, Kashino I, Saito T, Kishi R: The association between prenatal perfluoroalkyl substance exposure and symptoms of attention-deficit/hyperactivity disorder in 8-year-old children and the mediating role of thyroid hormones in the Hokkaido study. Environ Int 159, 2022
13. Ueda Y, Fujishige S, Goto T, Kimura S, Namatame N, Narugami M, Nakakubo S, Nakajima M, Egawa K, Kaneko N, Nakayama K, Hishimura N, Yamaguchi T, Nakamura A, Shiraishi H: Adrenal function during long‐term ACTH therapy for patients with developmental and epileptic encephalopathy. Epilepsia Open 7: 194-200, 2022
14. Kawashima S, Yuno A, Sano S, Nakamura A, Ishiwata K, Kawasaki T, Hosomichi K, Nakabayashi K, Akutsu H, Saitsu H, Fukami M, Usui T, Ogata T, Kagami M: Familial Pseudohypoparathyroidism Type IB Associated with an SVA Retrotransposon Insertion in the GNAS Locus. J Bone Miner Res37(10):1850-1859, 2022
15. Fuke T, Nakamura A, Inoue T, Kawashima S, Hara-Isono K, Matsubara K, Sano S, Yamazawa K, Fukami M, Ogata T, Kagami M: Frequency and clinical characteristics of distinct etiologies in patients with Silver-Russell syndrome diagnosed based on the Netchine-Harbison clinical scoring system. J Hum Genet 67(10): 607-611, 2022
16. Hara-Isono K, Nakamura A, Fuke T, Inoue T, Kawashima S, Matsubara K, Sano S, Yamazawa K, Fukami M, Ogata T, Kagami M: Pathogenic Copy Number and Sequence Variants in Children Born SGA With Short Stature Without Imprinting Disorders. J Clin Endocrinol Metab 107(8): e3121–e3133, 2022
17. Kobayashi I, Shimomura M, Ueki M, Takezaki S, Okura Y, Nawate M, Yamada M, Takahashi Y, Ariga T: Development of Graves' disease during drug-free remission of juvenile dermatomyositis. Mod Rheumatol Case Rep6(1): 55-58, 2022
18. Shimaa Abdrabou, Nariaki Toita, Shin Ichihara, Yusuke Tozawa, Michiko Takahashi, Shin-ichi Fujiwara, Toshifumi Ashida, Osamu Ohara, Tadashi Ariga, Atsushi Manabe, Mutsuko Konno, Masafumi Yamada. Absent XIAP expression in T cell blasts and causal XIAP mutations including non-coding deletion. Pediatr Int. 64-(1):e14892. 2022
19. Zineb Sbihi, Kay Tanita, Camille Bachelet, Christine Bole, Fabienne Jabot-Hanin, Frederic Tores, Marc Le Loch, Radi Khodr, Akihiro Hoshino, Christelle Lenoir, Matias Oleastro, Mariana Villa, Lucia Spossito.., Takashi Taga, Shimaa Abdrabou, Takeshi Isoda, Masafumi Yamada, Alejandro Palma, Hirokazu Kanegane, Sylvain Latour. Identification of germline non-coding deletions in XIAP gene causing XIAP deficiency reveals a key promoter sequence. J Clin Immunol.42, 559–571. 2022
20. Kuroko Y, Yoshihara H, Hosoya Y, Manabe A, Hasegawa D: Intrathecal therapy in acute lymphoblastic leukemia case with spinal deformity. Pediatr Int 64: e14845, 2022
21. Hama A, Hasegawa D, Manabe A, Nozawa K, Narita A, Muramatsu H, Kosaka Y, Kobayashi M, Koh K, Takahashi Y, Watanabe K, Ohara A, Ito M, Kojima S: Prospective validation of the provisional entity of refractory cytopenia of childhood, proposed by the World Health Organization. Br J Haematol 196: 1031-1039, 2022
22. Honda Y, Muramatsu H, Nanjo Y, Hirabayashi S, Meguro T, Yoshida N, Kakuda H, Ozono S, Wakamatsu M, Moritake H, Yasui M, Sano H, Manabe A, Sakashita K: A retrospective analysis of azacitidine treatment for juvenile myelomonocytic leukemia. Int J Hematol 115: 263-268, 2022
23. Buchmann S, Schrappe M, Baruchel A, Biondi A, Borowitz M, Campbell M, Cario G, Cazzaniga G, Escherich G, Harrison C, Heyman M, Hunger S, Kiss C, Liu HC, Locatelli F, Loh M, Manabe A, Mann G, Pieters R, Pui CH, Rives S, Schmiegelow K, Silverman L, Stary J, Vora A, Brown P: Remission, treatment failure, and relapse in pediatric ALL: An international consensus of the Ponte-di-Legno Consortium. Blood 139: 1785-1793, 2022
24. Hasegawa M, Sugiyama M, Terashita Y, Cho Y, Manabe A: Hepatoblastoma with bone/bone marrow metastasis in Li-Fraumeni syndrome patient. Pediatr Int 64(1), 2022
25. Tanaka Y, Urayama KY, Mori M, Arakawa Y, Hasegawa D, Noguchi Y, Yanagimachi M, Keino D, Ota S, Akahane K, Inukai T, Hangai M, Kawaguchi T, Takagi M, Koh K, Matsuda F, Manabe A: Prominence of NUDT15 genetic variation associated with 6-mercaptopurine tolerance in a genome-wide association study of Japanese children with acute lymphoblastic leukemia. Br J Haematol 199: 260-269, 2022
26. Yamaguchi S, Okamoto M, Ishi Y, Sawaya R, Motegi H, Sugiyama M, Harada T, Fujima N, Mori T, Hashimoto T, Takakuwa E, Manabe A, Kudo K, Aoyama H, Fujimura M. Long-term consequences of residual lesions after chemoradiotherapy in patients with germinoma at onset. J Neurosurg Pediatr, 30(5), 517-524. 2022
27. Yoshimoto-Suzuki YY, Hasegawa D, Hosoya Y, Saito G, Nagase K, Gunji M, Kobayashi K, Ishida Y, Manabe A, Ozawa M: Significance of active screening for detection of health problems in childhood cancer survivors. Front Pediatr 10: 947646, 2022
28. Kobayashi K, Ishida Y, Gunji M, Nagase K,Yoshimoto-Suzuki Y, Hosoya Y, Hasegawa D, Manabe A, Ohde S, Ozawa M: Factors related to employment in childhood cancer survivors in Japan: a preliminary study. Front Pediatr 10: 961935, 2022
29. Mitamura M, Kase S, Hirooka K, Endo H, Ito Y, Cho Y, Ishida S: Alterations of choroidal circulation and vascular morphology in a patient with chronic myeloid leukemia before and after chemotherapy. BMC Ophthalmol 22(1): 160, 2022
30. Nishida M, Sugita J, Iwai T, Sato M, Kudo Y, Omotehara S, Horie T, Sakano R, Hasegawa Y, Yasumoto A, Cho Y, Teshima T: Ultrasonographic scoring system of late-onset sinusoidal obstruction syndrome/veno-occlusive disease after hematopoietic stem cell transplantation. Bone Marrow Transplant 57(8): 1338-1340. 2022
31. Suekane A, Ichikawa T, Saito Y, Nakahata S, Morishita K: The CGRP Receptor Antagonist MK0974 Induces EVI1high AML Cell Apoptosis by Disrupting ERK Signaling. Anticancer Res 42: 4743-4752, 2022
32. Tanida R, Tsubouchi H, Yanagi S, Saito Y, Toshinai K, Miyazaki T, Takamura T, Nakazato M: GHS-R1a deficiency mitigates lipopolysaccharide-induced lung injury in mice via the downregulation of macrophage activity. Biochem Biophys Res Commun 589: 260-266, 2022
33. Kinoshita M, Yamada A, Saito Y, Kamimura S, Moritake H: Successful treatment with rituximab for autoimmune cytopenia after autologous hematopoietic stem cell transplantation. Pediatr int 64: e14975, 2022
34. Saito Y, Suwa Y, Kaneko Y, Tsujiwaki M, Odagawa Y: Kikuchi-Fujimoto disease following COVID-19 infection in a 7-year-old girl: a case report and literature review. Cureus 14: e26540, 2022
35. Norrish G, Cleary A, Field E, Cervi E, Boleti O, Ziółkowska L, Olivotto I, Khraiche D, Limongelli G, Anastasakis A, Weintraub R, Biagini E, Ragni L, Prendiville T, Duignan S, McLeod K, Ilina M, Fernandez A, Marrone C, Bökenkamp R, Baban A, Kubus P, Daubeney PEF, Sarquella-Brugada G, Cesar S, Klaassen S, Ojala TH, Bhole V, Medrano C, Uzun O, Brown E, Gran F, Sinagra G, Castro FJ, Stuart G, Yamazawa H, Barriales-Villa R, Garcia-Guereta L, Adwani S, Linter K, Bharucha T, Gonzales-Lopez E, Siles A, Rasmussen TB, Calcagnino M, Jones CB, De Wilde H, Kubo T, Felice T, Popoiu A, Mogensen J, Mathur S, Centeno F, Reinhardt Z, Schouvey S, Elliott PM, Kaski JP: Clinical Features and Natural History of Preadolescent Nonsyndromic Hypertrophic Cardiomyopathy. J Am Coll Cardiol 79(20): 1986-1997, 2022
36. Norrish G, Ding T, Field E, Cervi E, Ziółkowska L, Olivotto I, Khraiche D, Limongelli G, Anastasakis A, Weintraub R, Biagini E, Ragni L, Prendiville T, Duignan S, McLeod K, Ilina M, Fernández A, Marrone C, Bökenkamp R, Baban A, Kubus P, Daubeney PEF, Sarquella-Brugada G, Cesar S, Klaassen S, Ojala TH, Bhole V, Medrano C, Uzun O, Brown E, Gran F, Sinagra G, Castro FJ, Stuart G, Vignati G, Yamazawa H, Barriales-Villa R, Garcia-Guereta L, Adwani S, Linter K, Bharucha T, Garcia-Pavia P, Siles A, Rasmussen TB, Calcagnino M, Jones CB, De Wilde H, Kubo T, Felice T, Popoiu A, Mogensen J, Mathur S, Centeno F, Reinhardt Z, Schouvey S, O'Mahony C, Omar RZ, Elliott PM, Kaski JP: Relationship Between Maximal Left Ventricular Wall Thickness and Sudden Cardiac Death in Childhood Onset Hypertrophic Cardiomyopathy. Circ Arrhythm Electrophysiol 15(5): e010075, 2022
37. Yamazawa H, Takeda A, Izumi G, Komaki H, Nishino I: Sudden cardiac death prevention in an Emery-Dreifuss muscular dystrophy patient. Pediatr Int: e15204, 2022
38. Murakami T, Shiraishi M: What connects body height and flow-mediated vasodilation?. Hypertension Research 45(7): 1220, 2022
39. Murakami T, Shiraishi M: Pulse pressure amplification is one of the important factors evaluating peripheral blood pressure during exercise. Journal of Hypertension 40: 1245, 2022
40. Murakami T, Shiraishi M, Niwa K: Aortic root dilatation and aortic stiffness. Journal of Hypertension 40: 1431, 2022
41. Murakami T, Shiraishi M: The sex difference in the association of enhanced brachial-ankle pulse wave velocity and adverse cardiac remodeling; the possible background mechanism. Journal of Hypertension 40: 1432, 2022
42. Inai K, Inuzuka R, Ono H, Nii M, Ohtsuki S, Kurita Y, Takeda A, Hirono K, Takei K, Yasukouchi S, Yoshikawa T, Furutani Y, Shimada E, Shinohara T, Shinozaki T, Matsuyama Y, Senzaki H, Nakanishi T: Predictors of long-term mortality among perioperative survivors of Fontan operation. Eur Heart J 43(25): 2373-2384, 2022
43. Ohyama-Tamagake A, Kaneko K, Itami R, Nakano M, Namioka Y, Izumi R, Sato H, Suzuki H, Takeda A, Okazaki Y, Yatsuka Y, Abe T, Murayama K, Sugeno N, Misu T, Aoki M: Adult-onset Leigh Syndrome with a m.9176 T>C Mutation Manifested as Reversible Cerebral Vasoconstriction Syndrome. Intern Med, 2022 [online ahead of print].
44. Watanabe K, Maruo Y, Takeda A: Efficacy of cibenzoline for hypertrophic obstructive cardiomyopathy in paediatric patients with RAS/MAPK pathway syndromes. Cardiol Young: 1-3, 2022
45. Abe J, Honda M, Sasaki D, Taniguchi K, Izumi G, Furukawa T, Yamazawa H, Takei K, Takeda A: A geometrical pitfall of Area-Length method; -Is left ventricle volume evaluation of repaired Tetralogy of Fallot by angiocardiography accurate?. Heart Vessels 37(10): 1785-1791, 2022
46. Takahashi S, Segoe H, Kikuiri T, Maruo Y, Sato T, Watanabe Y, Jimei Z, Yoshimura Y, Ishiyama M, Takeda A, Yawaka Y, Shirakawa T: A rare case of multiple brain abscesses caused by apical periodontitis of deciduous teeth in congenital heart disease: a case report. BMC Oral Health 22(1): 261, 2022
47. Shimozawa H, Sato T, Osaka H, Takeda A, Miyauchi A, Omika N, Yada Y, Kono Y, Murayama K, Okazaki Y, Kishita Y, Yamagata T: A Case of Infantile Mitochondrial Cardiomyopathy Treated with a Combination of Low-Dose Propranolol and Cibenzoline for Left Ventricular Outflow Tract Stenosis. Int Heart J 63(5): 970-977, 2022
48. Chida-Nagai A, Tsujino I, Yakuwa S, Akagawa H, Tsujioka T, Taniguchi K, Sasaki O, Izumi G, Yamazawa H, Takeda A: A cardiac arrest case due to left coronary artery compression in congenital heart disease-associated pulmonary arterial hypertension. CJC Pediatric and Congenital Heart Disease, 2022 [online published]
49. Chida-Nagai A, Tsujioka T, Sasaki D, Izumi G, Yamazawa H, Takeda A: An Adolescent Patient With Idiopathic Pulmonary Arterial Hypertension Weaned Off Intravenous Epoprostenol Following Treatment With Selexipag: A Case Report. Front Pediatr, 2022
50. Chida-Nagai A,Sato H, Sato I, Shiraishi M, Sasaki D, Izumi G, Yamazawa H, Cho K, Manabe A, Takeda A: Risk factors for hospitalisation due to respiratory syncytial virus infection in children receiving prophylactic palivizumab. Eur J Pediatr 181(2): 539-547, 2022
51. Chiba Y, Izumi G,Takeda A: Atypical sites of twin atrioventricular nodes in a rare form of univentricular heart. Pacing Clin Electrophysiol 45(10): 1225-1228, 2022
52. Izumi G, Takeda A, Yamazawa H, Nagai A, Sasaki D, Sato I, Kato N, Tachibana T: Usefulness of Prolonged PR Interval to Predict Atrial Tachyarrhythmia Development Following Surgical Repair of Tetralogy of Fallot. IAm J Cardiol 184,127-132, 2022
53. Izumi G, Takeda A, Yamazawa H, Kato N, Kato H, Tachibana T, Sagae O, Yahagi R, Maeno M, Hoshino K, Saito H. Perioperative junctional ectopic tachycardia associated with congenital heart disease: risk factors and appropriate interventions. Heart Vessels 37: 1792-1800, 2022
54. Sasaki D, Abe J, Takeda A, Harashima H and Yamada Y: Transplantation of MITO cells, mitochondria activated cardiac progenitor cells, to the ischemic myocardium of mouse enhances the therapeutic effect. Scientific Reports 12(1): 4344, 2022
55. Yamada K, Takahata M, Ito M, Nagahama K, Iwata A, Endo T, Sudo H, Ishiguro N, Iwasaki N: Risk factors of multidrug-resistant pyogenic spondylitis in thoraco-lumbar spine: A retrospective study of 122 cases. J Orthop Sci 27(1): 95-100, 2022
56. Oka K, Matsumoto A, Tetsuka N, Morioka H, Iguchi M, Ishiguro N, Nagamori T, Takahashi S, Saito N, Tokuda K, Igari H, Fujikura Y, Kato H, Kanai S, Kusama F, Iwasaki H, Furuhashi K, Baba H, Nagao M, Nakanishi M, Kasahara K, Kakeya H, Chikumi H, Ohge H, Azuma M, Tauchi H, Shimono N, Hamada Y, Takajo I, Nakata H, Kawamura H, Fujita J, Yagi T; Japan Infection Prevention and Control Conference for National and Public University Hospitals: Clinical characteristics and treatment outcomes of carbapenem-resistant Enterobacterales infections in Japan. J Glob Antimicrob Resist: 247-252., 2022
57. Norrish G, Qu C, Field E, Cervi E, Khraiche D, Klaassen S, Ojala TH, Sinagra G, Yamazawa H, Marrone C, Popoiu A, Centeno F, Schouvey S, Olivotto I, Day SM, Colan S, Rossano J, Wittekind SG, Saberi S, Russell M, Helms A, Ingles J, Semsarian C, Elliott PM, Ho CY, Omar RZ, Kaski JP: External validation of the HCM Risk-Kids model for predicting sudden cardiac death in childhood hypertrophic cardiomyopathy. Eur J Prev Cardiol 29(4): 678-686, 2022
58. Tsujioka T, Sasaki D, Takeda A, Harashima H, Yamada Y: Resveratrol-Encapsulated Mitochondria-Targeting Liposome Enhances Mitochondrial Respiratory Capacity in Myocardial Cells. Int J Mol Sci 23(1): 112, 2022
59. Yamazawa H,Takeda A, Izumi G: Challenges in the primary prevention of sudden cardiac death in hypertrophic cardiomyopathy in the young. Cardiol Young 32(1): 156-157, 2022
60. Kato M, Kada A, Shiraishi H, Tohyama J, Nakagawa E, Takahashi Y, Akiyama T, Kakita A, Miyake N, Fujita A, Saito AM, Inoue Y: Sirolimus for epileptic seizures associated with focal cortical dysplasia type II. Ann Clin Transl Neurol 9(2): 181-192, 2022
61. Inoue Y, Hamano SI, Hayashi M, Sakuma H, Hirose S, Ishii A, Honda R, Ikeda A, Imai K, Jin K, Kada A, Kakita A, Kato M, Kawai K, Kawakami T, Kobayashi K, Matsuishi T, Matsuo T, Nabatame S, Okamoto N, Ito S, Okumura A, Saito A, Shiraishi H, Shirozu H, Saito T, Sugano H, Takahashi Y, Yamamoto H, Fukuyama T, Kuki I: Burden of seizures and comorbidities in patients with epilepsy: a survey based on the tertiary hospital-based Epilepsy Syndrome Registry in Japan. Epileptic Disord 24(1): 82-94, 2022
62. Okanishi T, Fujii Y, Sakuma S, Shiraishi H, Motoi H, Yazaki K, Enoki H, Fujimoto A: Lacosamide monotherapy for the treatment of childhood epilepsy with centrotemporal spikes. Brain Dev 44(6): 380-385, 2022
63. Sueda K, Hashimoto R, Ueda T: Convergent validity of the developmental coordination disorder checklist using soft neurological signs. Brain Dev 44(1): 17-29, 2022

論文（邦文）

1. 長　和俊、西村千織、朴澤博之、橋本孝史、山本ルイス: 北海道における不規則なRSウイルス感染症流行パターンの解析. 小児科診療(0386-9806)85(11): 1477-1482, 2022.11
2. 印南裕貴、馬場志郎、中澤温子、大塚沙樹、武野　亨、吉永大介、松田浩一、赤木健太郎、平田拓也、井出雄二郎、池田　義、長　和俊、滝田順子: Ebstein病根治術後も呼吸不全が遷延し、間質性肺疾患の合併が判明した男児例. 小児科臨床(0021-518X)75(3): 431-437, 2022.06
3. 古瀬優太: 子ども虐待対応のための基礎知識と医療の役割(日本子ども虐待医学会推薦総説). 日本小児科学会雑誌(0001-6543)126(5): 769-782, 2022.05
4. 長　和俊: 胎児肺の成長・発達と出生後の呼吸の適応生理. with Neo 2022秋季増刊: 10-15, 2022.09
5. 古瀬優太: 新生児の適応生理「呼吸」. with NEO(2434-4540)35(5): 674-685, 2022.10
6. 長　和俊:「肺胞蛋白症診療ガイドライン2022」：「先天性肺胞蛋白症／遺伝性肺胞蛋白症（CPAP/HPAP）および肺サーファクタント関連遺伝子変異由来での病態、診断、治療、合併症、予後」https://www.jrs.or.jp/publication/file/pap2022.pdf
7. 外木秀文: 先天異常　病気が見えるVol 15. 小児科: 156-173, 2022, メディックメディア 東京
8. 竹内千仙、井手友美、植田紀美子、大石　智、北畠康司、黒柳裕一、小松知子、玉井　浩、外木秀文、橋本洋之: ダウン症成人診療ガイドライン翻訳プロジェクト. 日本語版　成人期ダウン症診療ガイドライン　Web公開　日本ダウン症学会, 2022
9. 長谷河昌孝、長　祐子、大久保淳、寺下友佳代、杉山未奈子、井口晶裕、河北一誠、荒　桃子、本多昌平、若林健人、高桑恵美、外木秀文、真部　淳: ウィリアムズ症候群の男児に発症したバーキットリンパ腫. 小児血液がん学会雑誌59(3): 292–295, 2022
10. 大園秀一、石田也寸志、前田美穂、大植孝治、上別府圭子、清谷知賀子、竹之内直子、長　祐子、湯坐有希、家原知子、宮村能子、檜山英三、松本公一、大賀正一 (日本小児血液・がん学会長期フォローアップ・移行期医療委員会): 小児期発症血液・腫瘍性疾患の成人への移行期支援に関する基本的姿勢(解説). 日本小児血液・がん学会雑誌(2187-011X)59(1): 58-65
11. 白石秀明: 脳波の読み方 -up to date 自然終息性（self-limited）てんかん: CLINICAL NEUROSCIENCE: 468-473, 中外医学社, 東京, 2022
12. 植田佑樹、白石秀明: 脳の形態異常. 周産期医学必修知識　第9版: 東京医学社, 東京, 2022
13. 石黒信久: 治療法の再整理とアップデートのために専門家による私の治療　ライム病. 日本医事新報 5143: 43-44 , 2022
14. 石黒信久、田村祐子: 【新型コロナとインフルエンザ　同時流行に備えるために再確認しておきたいこと】感染防御(PART.6)　インフルエンザと新型コロナの感染防御でおさえておきたいこと. Expert Nurse 38(13): 36-42 , 2022
15. 三鴨廣繁、多屋馨子、石黒信久、岩田　敏、内田美保、岡田賢司、金井信一郎、豊川真弘、中野貴司、藤村　茂、山岸由佳: 一般社団法人日本環境感染学会ワクチン委員会　医療関係者のためのワクチンガイドライン(第3版)追補版　新型コロナワクチン. 日本環境感染学会誌 37(1): S1-S4, 2022
16. 長　和俊: 新生児の分娩損傷. 産科と婦人科89巻増刊: 59-62, 2022.03
17. 中村明枝：内分泌関連疾患の遺伝学と遺伝学的検査「内分泌疾患のジェネティクス」. 小児内分泌学　改訂第3版（日本小児内分泌学会［編］）：診断と治療社. 2022
18. 中村明枝：主要兆候からのアプローチ「高血糖」. 小児内分泌学　改訂第3版（日本小児内分泌学会［編］）：診断と治療社. 2022
19. 森川俊太郎：内分泌救急処置「低血糖」. 小児内分泌学　改訂第3版（日本小児内分泌学会［編］）：診断と治療社. 2022

過去の業績

• 令和3（2021）年度
• 令和2（2020）年度
• 平成31（2019）年度
• 平成30（2018）年度
• 平成29（2017）年度
• 平成28（2016）年度
• 平成27（2015）年度
• 平成26（2014）年度
• 平成25（2013）年度
• 平成24（2012）年度
• 平成23（2011）年度
• 平成22（2010）年度
• 平成21（2009）年度
• 平成20（2008）年度
• 平成19（2007）年度
• 平成18（2006）年度
• 平成17（2005）年度
• 平成16（2004）年度